Ethyl 2,2-difluoro-2-(quinolin-6-yl)acetate

Modify Date: 2024-01-16 09:24:49

Ethyl 2,2-difluoro-2-(quinolin-6-yl)acetate Structure
Ethyl 2,2-difluoro-2-(quinolin-6-yl)acetate structure
Common Name Ethyl 2,2-difluoro-2-(quinolin-6-yl)acetate
CAS Number 943541-40-0 Molecular Weight 251.22900
Density 1.269g/cm3 Boiling Point 348.7ºC at 760 mmHg
Molecular Formula C13H11F2NO2 Melting Point N/A
MSDS N/A Flash Point 164.7ºC

 Names

Name ethyl 2,2-difluoro-2-quinolin-6-ylacetate
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.269g/cm3
Boiling Point 348.7ºC at 760 mmHg
Molecular Formula C13H11F2NO2
Molecular Weight 251.22900
Flash Point 164.7ºC
Exact Mass 251.07600
PSA 39.19000
LogP 2.88970
Index of Refraction 1.546

 Safety Information

HS Code 2933499090

 Synthetic Route

~72%

Ethyl 2,2-difluoro-2-(quinolin-6-yl)acetate Structure

Ethyl 2,2-diflu...

CAS#:943541-40-0

Literature: JANSSEN PHARMACEUTICA NV Patent: WO2008/155378 A1, 2008 ; Location in patent: Page/Page column 71-72 ;

~51%

Ethyl 2,2-difluoro-2-(quinolin-6-yl)acetate Structure

Ethyl 2,2-diflu...

CAS#:943541-40-0

Literature: VERTEX PHARMACEUTICALS INCORPORATED; LI, Pan; WAAL, Nathan; RONKIN, Steven; TANG, Qing; LAUFFER, David Patent: WO2010/138663 A1, 2010 ; Location in patent: Page/Page column 25-26 ; WO 2010/138663 A1

~%

Ethyl 2,2-difluoro-2-(quinolin-6-yl)acetate Structure

Ethyl 2,2-diflu...

CAS#:943541-40-0

Literature: US2011/294849 A1, ;

 Customs

HS Code 2933499090
Summary 2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

ethyl 2,2-difluoro-2-(quinolin-6-yl)acetate
ethyl 2,2-difluoro(quinolin-6-yl)acetate
difluoro-quinolin-6-yl-acetic acid ethyl ester
2,2-difluoro-2-(quinolin-6-yl)acetic acid ethyl ester
ETHYL DIFLUORO(QUINOLIN-6-YL)ACETATE
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