3-chloro-4-[[(2R)-4-[4-fluoro-2-(trifluoromethyl)phenyl]-2-methyl-1-piperazinyl]sulfonyl]-Benzonitrile structure
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Common Name | 3-chloro-4-[[(2R)-4-[4-fluoro-2-(trifluoromethyl)phenyl]-2-methyl-1-piperazinyl]sulfonyl]-Benzonitrile | ||
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CAS Number | 946400-19-7 | Molecular Weight | 461.86 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C19H16ClF4N3O2S | Melting Point | N/A | |
MSDS | N/A | Flash Point | N/A |
Use of 3-chloro-4-[[(2R)-4-[4-fluoro-2-(trifluoromethyl)phenyl]-2-methyl-1-piperazinyl]sulfonyl]-Benzonitrile3-chloro-4-[[(2R)-4-[4-fluoro-2-(trifluoromethyl)phenyl]-2-methyl-1-piperazinyl]sulfonyl]-Benzonitrile shows inhibitory activities for hHSD1 and mHSD1 with IC50s of 16 nM and 10 nM. |
Name | 3-chloro-4-[[(2R)-4-[4-fluoro-2-(trifluoromethyl)phenyl]-2-methyl-1-piperazinyl]sulfonyl]-Benzonitrile |
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Description | 3-chloro-4-[[(2R)-4-[4-fluoro-2-(trifluoromethyl)phenyl]-2-methyl-1-piperazinyl]sulfonyl]-Benzonitrile shows inhibitory activities for hHSD1 and mHSD1 with IC50s of 16 nM and 10 nM. |
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References | 1. Wan ZK, et al. Efficacious 11beta-hydroxysteroid dehydrogenase type I inhibitors in the diet-induced obesity mouse model. J Med Chem. 2009 Sep 10;52(17):5449-61. |
Molecular Formula | C19H16ClF4N3O2S |
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Molecular Weight | 461.86 |