5-hydroxy Thiabendazole

Modify Date: 2024-01-09 21:08:02

5-hydroxy Thiabendazole Structure
5-hydroxy Thiabendazole structure
Common Name 5-hydroxy Thiabendazole
CAS Number 948-71-0 Molecular Weight 217.25
Density 1.535g/cm3 Boiling Point 525.6ºC at 760mmHg
Molecular Formula C10H7N3OS Melting Point N/A
MSDS Chinese USA Flash Point 271.7ºC
Symbol GHS07 GHS09
GHS07, GHS09
Signal Word Warning

 Use of 5-hydroxy Thiabendazole


5-Hydroxythiabendazole (5-OHTBZ) is a biomarker of Thiabendazole (HY-B0263) exposure[1].

 Names

Name 5-Hydroxy Thiabendazole
Synonym More Synonyms

 5-hydroxy Thiabendazole Biological Activity

Description 5-Hydroxythiabendazole (5-OHTBZ) is a biomarker of Thiabendazole (HY-B0263) exposure[1].
Related Catalog
References

[1]. STONE OJ, et al. COMPARISON OF THIABENDAZOLE AND 5-HYDROXY-THIABENDAZOLE (FOR ANTHELMINTIC EFFECT). J Invest Dermatol. 1965 Aug;45:132-3.  

 Chemical & Physical Properties

Density 1.535g/cm3
Boiling Point 525.6ºC at 760mmHg
Molecular Formula C10H7N3OS
Molecular Weight 217.25
Flash Point 271.7ºC
Exact Mass 217.03100
PSA 90.04000
LogP 2.39200
Index of Refraction 1.783
Storage condition 0-6°C

 Safety Information

Symbol GHS07 GHS09
GHS07, GHS09
Signal Word Warning
Hazard Statements H302-H400
Precautionary Statements P273
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xn,N
Risk Phrases 22-50/53
Safety Phrases 60-61
RIDADR UN 3077
Packaging Group III
Hazard Class 9
HS Code 2934999090

 Synthetic Route

~%

5-hydroxy Thiabendazole Structure

5-hydroxy Thiab...

CAS#:948-71-0

Literature: Xenobiotica, , vol. 26, # 7 p. 765 - 778

 Precursor & DownStream

Precursor  1

DownStream  1

 Customs

HS Code 2934999090
Summary 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Articles16

More Articles
Multi-residue Determination of Polar Veterinary Drugs in Livestock and Fishery Products by Liquid Chromatography/Tandem Mass Spectrometry.

J. AOAC Int. 98(1) , 230-47, (2015)

Residues of 37 polar veterinary drugs belonging to six families (quinolones, tetracyclines, macrolides, lincosamides, sulfonamides, and others) in livestock and fishery products were determined using ...

Evidence for cytochrome P4501A2-mediated protein covalent binding of thiabendazole and for its passive intestinal transport: use of human and rabbit derived cells.

Chem. Biol. Interact. 127(2) , 109-24, (2000)

Thiabendazole (TBZ), an anthelmintic and fungicide benzimidazole, was recently demonstrated to be extensively metabolized by cytochrome P450 (CYP) 1A2 in man and rabbit, yielding 5-hydroxythiabendazol...

In vitro and in silico identification and characterization of thiabendazole as a mechanism-based inhibitor of CYP1A2 and simulation of possible pharmacokinetic drug-drug interactions.

Drug Metab. Dispos. 37 , 1286-1294, (2009)

Thiabendazole (TBZ) and its major metabolite 5-hydroxythiabendazole (5OH-TBZ) were screened for potential time-dependent inhibition (TDI) against CYP1A2. Screen assays were carried out in the absence ...

 Synonyms

2-(1,3-thiazol-4-yl)-3H-benzimidazol-5-ol
Top Suppliers:I want be here


Get all suppliers and price by the below link:

5-hydroxy Thiabendazole suppliers

5-hydroxy Thiabendazole price