GKT136901

Modify Date: 2024-02-02 13:35:48

GKT136901 Structure
GKT136901 structure
Common Name GKT136901
CAS Number 955272-06-7 Molecular Weight 366.80100
Density N/A Boiling Point N/A
Molecular Formula C19H15ClN4O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of GKT136901


GKT136901 is a potent, selective and orally active inhibitor of NADPH oxidase (NOX1/4), with Kis of 160 and 165 nM, respectively. GKT136901 also is a selective and direct scavenger of peroxynitrite. GKT136901 can be used for the research of diabetic nephropathy, stroke, and neurodegeneration. GKT136901 also has anti-inflammatory activity.

 Names

Name 2-(2-Chlorophenyl)-4-methyl-5-(pyridin-2-ylmethyl)-1H-pyrazolo[4,3-c]pyridine-3,6(2H,5H)-dione
Synonym More Synonyms

 Chemical & Physical Properties

Molecular Formula C19H15ClN4O2
Molecular Weight 366.80100
Exact Mass 366.08800
PSA 72.68000
LogP 2.88560

 Safety Information

HS Code 2933990090

 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

2-(2-chlorophenyl)-4-methyl-5-(pyridin-2-ylmethyl)-1H-pyrazolo[4,3-c]pyridine-3,6-dione