PQ1 Succinate
PQ1 Succinate structure
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Common Name | PQ1 Succinate | ||
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| CAS Number | 955995-51-4 | Molecular Weight | 523.502 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C25H28F3N3O6 | Melting Point | N/A | |
| MSDS | USA | Flash Point | N/A | |
Use of PQ1 SuccinatePQ1 Succinate is a gap junction enhancer. It acts by restoring GJIC and increasing connexin expression in breast cancer cell lines while not affecting normal mammary cells. |
| Name | MFCD22666397 |
|---|---|
| Synonym | More Synonyms |
| Molecular Formula | C25H28F3N3O6 |
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| Molecular Weight | 523.502 |
| Exact Mass | 523.192993 |
| RIDADR | NONH for all modes of transport |
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Gap Junction Enhancer Potentiates Cytotoxicity of Cisplatin in Breast Cancer Cells.
J. Cancer Sci. Ther. 4(11) , 371-378, (2012) Cisplatin is one of the most widely used anti-cancer drugs due to its ability to damage DNA and induce apoptosis. However, increasing reports of side effects and drug resistance indicate the limitatio... |
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PQ1, a quinoline derivative, induces apoptosis in T47D breast cancer cells through activation of caspase-8 and caspase-9.
Apoptosis 18(9) , 1071-82, (2013) Apoptosis, a programmed cell death, is an important control mechanism of cell homeostasis. Deficiency in apoptosis is one of the key features of cancer cells, allowing cells to escape from death. Acti... |
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The effect of the PQ1 anti-breast cancer agent on normal tissues.
Anticancer Drugs 23(9) , 897-905, (2012) Gap junctions are intercellular channels connecting adjacent cells, allowing cells to transport small molecules. The loss of gap junctional intercellular communication (GJIC) is one of the important h... |
| N1-[6-Methoxy-4-methyl-5-[3-(trifluoromethyl)phenoxy]-8-quinolinyl]-1,3-propanediamine butanedioic acid salt |
| PQ1 succinic acid salt |
| 1,3-Propanediamine, N1-[6-methoxy-4-methyl-5-[3-(trifluoromethyl)phenoxy]-8-quinolinyl]-, butanedioate (1:1) |
| Succinic acid - N-{6-methoxy-4-methyl-5-[3-(trifluoromethyl)phenoxy]-8-quinolinyl}-1,3-propanediamine (1:1) |
| MFCD22666397 |
| PQ1 succinate |