DL-Glutamic acid-d3

Modify Date: 2024-01-18 19:30:47

DL-Glutamic acid-d3 Structure
DL-Glutamic acid-d3 structure
Common Name DL-Glutamic acid-d3
CAS Number 96927-56-9 Molecular Weight 150.148
Density 1.4±0.1 g/cm3 Boiling Point 333.8±32.0 °C at 760 mmHg
Molecular Formula C5H6D3NO4 Melting Point 185 °C (dec)(lit.)
MSDS USA Flash Point 155.7±25.1 °C

 Use of DL-Glutamic acid-d3


DL-Glutamic acid-d3 is the deuterium labeled DL-Glutamic acid. DL-Glutamic acid is the conjugate acid of Glutamic acid, which acts as a fundamental metabolite. Comparing with the second phase of polymorphs α and β L-Glutamic acid, DL-Glutamic acid presents better stability[1].

 Names

Name dl-glutamic-2,4,4-d3 acid
Synonym More Synonyms

 DL-Glutamic acid-d3 Biological Activity

Description DL-Glutamic acid-d3 is the deuterium labeled DL-Glutamic acid. DL-Glutamic acid is the conjugate acid of Glutamic acid, which acts as a fundamental metabolite. Comparing with the second phase of polymorphs α and β L-Glutamic acid, DL-Glutamic acid presents better stability[1].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 333.8±32.0 °C at 760 mmHg
Melting Point 185 °C (dec)(lit.)
Molecular Formula C5H6D3NO4
Molecular Weight 150.148
Flash Point 155.7±25.1 °C
Exact Mass 150.071991
PSA 100.62000
LogP -1.43
Vapour Pressure 0.0±1.5 mmHg at 25°C
Index of Refraction 1.522
Storage condition -20C

 Synonyms

(2,4,4-H)Glutamic acid
Glutamic-2,4,4-d acid