α-Me-5-HT

Modify Date: 2024-01-11 00:18:29

α-Me-5-HT structure	Common Name	α-Me-5-HT
	CAS Number	97469-12-0	Molecular Weight	306.31400
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₅H₁₈N₂O₅	Melting Point	191 - 193 °C
	MSDS	USA	Flash Point	N/A

Use of α-Me-5-HT

α-methyl Serotonin (maleate) is an agonist of serotonin (5-HT) receptors. It binds selectively to 5-HT1A, 5-HT1B, 5-HT1C, and 5-HT1D receptors over 5-HT1E receptors. It is also selective for 5-HT2B and 5-HT2C receptors over 5-HT2A receptors. α-methyl Serotonin potentiates motor neuron depolarizations induced by NMDA in the presence of the NMDA receptor antagonist memantine. It also increases dopamine release in a dose-dependent manner. α-methyl Serotonin increases systolic blood pressure and transiently increases heart rate.

Name	3-(2-aminopropyl)-1H-indol-5-ol,(Z)-but-2-enedioic acid
Synonym	More Synonyms

Melting Point	191 - 193 °C
Molecular Formula	C₁₅H₁₈N₂O₅
Molecular Weight	306.31400
Exact Mass	306.12200
PSA	136.64000
LogP	2.17530
Storage condition	20°C

α-Me-5-HT MSDS(Chinese)

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR	NONH for all modes of transport
HS Code	2933990090

HS Code	2933990090
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

5-HT1 and 5-HT2 binding profiles of the serotonergic agents alpha-methylserotonin and 2-methylserotonin.

J. Med. Chem. 33 , 755-758, (1990)

alpha-Methyl-5-hydroxytryptamine (alpha-Me-5-HT; 2) and 2-methyl-5-hydroxytryptamine (2-Me-5-HT; 3) are considered to be 5-HT2-selective and 5-HT3-selective agents, respectively. These agents were syn...

Serotonin via 5-HT1B and 5-HT2B receptors stimulates anion secretion in the rat epididymal epithelium.

J. Physiol. 519 , 519, (1999)

1. The short-circuit current (Isc) technique was used to study the role of 5-hydroxytryptamine (5-HT) in the regulation of anion secretion in cultured rat cauda epididymal epithelia. 2. 5-HT, the 5-HT...

Effects of serotonin-1 and serotonin-2 receptor agonists on neuronal activity in the nucleus tractus solitarius.

J. Auton. Nerv. Syst. 56 , 119-124, (1995)

Spontaneous neuronal activity in the solitary tract nucleus was recorded extracellularly in a brain slice preparation during bath-application of 5-HT1 and 5-HT2 receptor-selective agonists and antagon...

|A-Methylserotonin maleate salt

2-methyl-5-HT

HMS3262F07