CHEMICAL IDENTIFICATION
-
RTECS NUMBER :
-
KG2940000
-
CHEMICAL NAME :
-
Estra-4,9-dien-3-one, 11-(4-(dimethylamino)phenyl)-17-hydroxy-17-(3-hydroxy -1-propenyl)-, (11-beta,17-beta,17(Z))-
-
CAS REGISTRY NUMBER :
-
97747-88-1
-
LAST UPDATED :
-
199612
-
DATA ITEMS CITED :
-
3
-
MOLECULAR FORMULA :
-
C29-H37-N-O3
-
MOLECULAR WEIGHT :
-
447.67
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
-
TYPE OF TEST :
-
TDLo - Lowest published toxic dose
-
ROUTE OF EXPOSURE :
-
Oral
-
DOSE :
-
1250 ug/kg
-
SEX/DURATION :
-
female 10 day(s) after conception
-
TOXIC EFFECTS :
-
Reproductive - Fertility - abortion
-
REFERENCE :
-
BIREBV Biology of Reproduction. (Soc. for the Study of Reproduction, 309 W. Clark St., Champaign, IL 61820) V.1- 1969- Volume(issue)/page/year: 40,549,1989
-
TYPE OF TEST :
-
TDLo - Lowest published toxic dose
-
ROUTE OF EXPOSURE :
-
Subcutaneous
-
DOSE :
-
45 mg/kg
-
SEX/DURATION :
-
female 5-7 day(s) after conception
-
TOXIC EFFECTS :
-
Reproductive - Maternal Effects - other effects Reproductive - Fertility - pre-implantation mortality (e.g. reduction in number of implants per female; total number of implants per corpora lutea) Reproductive - Fertility - other measures of fertility
-
REFERENCE :
-
JRPFA4 Journal of Reproduction and Fertility. (Biochemical Soc. Book Depot, POB 32, Commerce Way, Colchester, Essex CO2 8HP, UK) V.1- 1960- Volume(issue)/page/year: 83,73,1988
-
TYPE OF TEST :
-
TDLo - Lowest published toxic dose
-
ROUTE OF EXPOSURE :
-
Intramuscular
-
DOSE :
-
37500 ug/kg
-
SEX/DURATION :
-
female 24-26 day(s) after conception
-
TOXIC EFFECTS :
-
Reproductive - Fertility - abortion
-
REFERENCE :
-
BIREBV Biology of Reproduction. (Soc. for the Study of Reproduction, 309 W. Clark St., Champaign, IL 61820) V.1- 1969- Volume(issue)/page/year: 38,528,1988
|