Adipokinetic Hormone II (Locusta migratoria)

Modify Date: 2024-01-12 22:43:59

Adipokinetic Hormone II (Locusta migratoria) Structure
Adipokinetic Hormone II (Locusta migratoria) structure
Common Name Adipokinetic Hormone II (Locusta migratoria)
CAS Number 98968-94-6 Molecular Weight 903.98000
Density N/A Boiling Point N/A
Molecular Formula C43H57N11O11 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Adipokinetic Hormone II (Locusta migratoria)


Adipokinetic hormone II (Locusta migratoria) (Lom-AKH-II) is a insect adipokinetic hormone (AKH), enhances fat body cAMP levels in vitro. Insect adipokinetic hormones (AKHs) controls flight-directed mobilization of carbohydrate and lipid from fat body stores, which depends on AKH receptor(s) coupling to cAMP formation and glycogen phosphorylase activation via the stimulatory guanine nucleotide-binding protein (Gs)[1][3].

 Names

Name L-Tryptophanamide, 5-oxo-L-prolyl-L-leucyl-L-asparaginyl-L-phenylalanyl-L-seryl-L-alanylglycyl
Synonym More Synonyms

  Biological Activity

Description Adipokinetic hormone II (Locusta migratoria) (Lom-AKH-II) is a insect adipokinetic hormone (AKH), enhances fat body cAMP levels in vitro. Insect adipokinetic hormones (AKHs) controls flight-directed mobilization of carbohydrate and lipid from fat body stores, which depends on AKH receptor(s) coupling to cAMP formation and glycogen phosphorylase activation via the stimulatory guanine nucleotide-binding protein (Gs)[1][3].
Related Catalog
In Vitro Adipokinetic hormone II (Locusta migratoria) (radiolabeled; 1 pmol in 10 μL of 10% methanol; 30 min on ice, and repeated for 2 h at 30 ℃) shows no association with one of the larger protein components, indicating a lack of separate transporting or carrier protein in the hemolymph[1]. Adipokinetic hormones (AKHs) are known to be involved in insect immunity and shows the mechanism of metabolic stimulation, leading a significant increase in carbon dioxide production, and efficacy increase of toxins produced by I. fumosorosea in the cockroach's body[2]. Adipokinetic hormone II is more effective than hormone I in bringing about an accumulation of cAMP in the fat body[4].
In Vivo Adipokinetic hormone II (Locusta migratoria) (1 pmol in 10 μL of 10% methanol; injection) plays its own biol. role in the overall syndrome of insect flight, with different half-lives of 40 min and 37 min during rest and flight, respectively[1].

 Chemical & Physical Properties

Molecular Formula C43H57N11O11
Molecular Weight 903.98000
Exact Mass 903.42400
PSA 355.00000
LogP 1.14140

 Synonyms

Chromatophorotropin, red-pigment-concentrating (Pandalus borealis) 6-L-alanine-
ADIPOKINETIC HORMONE II (LOCUSTA MIGRATORIA)
Lom-AKH-2
ADIPOKINETIC HORMONE II
Adipokinetic hormone II (Locusta migratoria)
Locust adipokinetic hormone II
Lom-AKH-II