(-)-n-methylphysostigmine

Modify Date: 2024-04-05 19:19:34

(-)-n-methylphysostigmine Structure
(-)-n-methylphysostigmine structure
Common Name (-)-n-methylphysostigmine
CAS Number 103877-07-2 Molecular Weight 289.37300
Density 1.152g/cm3 Boiling Point 406.7ºC at 760 mmHg
Molecular Formula C16H23N3O2 Melting Point N/A
MSDS USA Flash Point 199.8ºC

 Names

Name [(3aR,8bS)-3,4,8b-trimethyl-2,3a-dihydro-1H-pyrrolo[2,3-b]indol-7-yl] N,N-dimethylcarbamate
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.152g/cm3
Boiling Point 406.7ºC at 760 mmHg
Molecular Formula C16H23N3O2
Molecular Weight 289.37300
Flash Point 199.8ºC
Exact Mass 289.17900
PSA 36.02000
LogP 2.11900
Appearance of Characters solid | white
Vapour Pressure 7.97E-07mmHg at 25°C
Index of Refraction 1.566
Storage condition 2-8°C
Water Solubility H2O: 1.9 mg/mL

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR UN 1544 6.1/PG 2
WGK Germany 3

 Articles4

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Anti-proliferative effect and induction of apoptosis in androgen-independent human prostate cancer cells by 1,5-bis(2-hydroxyphenyl)-1,4-pentadiene-3-one.

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Curcumin has poor in vivo absorption and bioavailability, highlighting a need for new curcumin analogues with better characteristics in these aspects. The aim of this study is to determine the anti-ca...

Levosimendan inhibits peroxidation in hepatocytes by modulating apoptosis/autophagy interplay.

PLoS ONE 10(4) , e0124742, (2015)

Levosimendan protects rat liver against peroxidative injuries through mechanisms related to nitric oxide (NO) production and mitochondrial ATP-dependent K (mitoKATP) channels opening. However, whether...

Inhibition of acetylcholinesterase from electric eel by (-)-and (+)-physostigmine and related compounds.

FEBS Lett. 201 , 190-192, (1986)

Unnatural (+)-physostigmine (2) inhibited acetylcholinesterase (AChE) from electric eel considerably less than natural (-)-physostigmine (1), but 2 may because of its possible lower toxicity still be ...

 Synonyms

Physostigmine analog 33