Ro 19-1400

Modify Date: 2024-03-07 15:00:38

Ro 19-1400 Structure
Ro 19-1400 structure
Common Name Ro 19-1400
CAS Number 122937-55-7 Molecular Weight 616.85000
Density N/A Boiling Point N/A
Molecular Formula C31H56N2O8S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Ro 19-1400


Ro 19-1400 is a platelet-activating factor antagonist that directly inhibits immunoglobulin E-dependent mediator release[1].

 Names

Name [(2R)-2-methoxycarbonyloxy-3-(octadecylcarbamoyloxy)propyl] 4-(1,3-thiazol-3-ium-3-yl)butanoate,hydroxide
Synonym More Synonyms

 Ro 19-1400 Biological Activity

Description Ro 19-1400 is a platelet-activating factor antagonist that directly inhibits immunoglobulin E-dependent mediator release[1].
Related Catalog
References

[1]. M. Pretolani, et al. Limited interference of specific Paf antagonists with hyper-responsiveness to Paf itself of lungs from actively sensitized guinea-pigs.Br J Pharmacol. 1989 Jun; 97(2): 433–442.

 Chemical & Physical Properties

Molecular Formula C31H56N2O8S
Molecular Weight 616.85000
Exact Mass 616.37600
PSA 147.83000
LogP 7.51090

 Synonyms

3-(4-(2-((Methoxycarbonyl)oxy)-3-(((octadecylamino)carbonyl)oxy)propoxy)-4-oxobutyl)-,hydroxide,(R)-thiazolium
Thiazolium,3-(4-(2-((methoxycarbonyl)oxy)-3-(((octadecylamino)carbonyl)oxy)propoxy)-4-oxobutyl)-,hydroxide,(R)
Ro-19-1400
[(2R)-2-methoxycarbonyloxy-3-(octadecylcarbamoyloxy)propyl] 4-(1,3-thiazol-3-ium-3-yl)butanoate hydroxide