D(-)-2-Aminobutyric acid-d6

Modify Date: 2024-07-22 19:03:16

D(-)-2-Aminobutyric acid-d6 Structure
D(-)-2-Aminobutyric acid-d6 structure
Common Name D(-)-2-Aminobutyric acid-d6
CAS Number 1276197-57-9 Molecular Weight 109.16
Density N/A Boiling Point N/A
Molecular Formula C4H3D6NO2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of D(-)-2-Aminobutyric acid-d6


D(-)-2-Aminobutyric acid-d6 is the deuterium labeled D(-)-2-Aminobutyric acid. D(-)-2-Aminobutyric acid is a substrate of D-amino acid oxidase.

 Names

Name D(-)-2-Aminobutyric acid-d6

 D(-)-2-Aminobutyric acid-d6 Biological Activity

Description D(-)-2-Aminobutyric acid-d6 is the deuterium labeled D(-)-2-Aminobutyric acid. D(-)-2-Aminobutyric acid is a substrate of D-amino acid oxidase.
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

[2]. Yagi K, et al. Spectroscopic demonstration of an initial stage of the complex of D-amino acid oxidase and its substrate D-alpha-aminobutyric acid. Biochem Biophys Res Commun. 1980 Nov 28;97(2):370-4.

 Chemical & Physical Properties

Molecular Formula C4H3D6NO2
Molecular Weight 109.16