1-(2,3-Dideoxy-β-D-erythro-hexo pyranosyl)cytosine

Modify Date: 2024-02-01 15:06:56

1-(2,3-Dideoxy-β-D-erythro-hexo pyranosyl)cytosine Structure
1-(2,3-Dideoxy-β-D-erythro-hexo pyranosyl)cytosine structure
 Common Name 1-(2,3-Dideoxy-β-D-erythro-hexo pyranosyl)cytosine
CAS Number 136020-18-3 Molecular Weight 257.24
Density 1.63g/cm3 Boiling Point 491.8ºC at 760mmHg
Molecular Formula C10H15N3O5 Melting Point N/A
MSDS N/A Flash Point 251.3ºC

 Use of 1-(2,3-Dideoxy-β-D-erythro-hexo pyranosyl)cytosine


1-(2,3-Dideoxy-β-D-erythro-hexo pyranosyl)cytosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name 4-amino-1-[(2R,5S,6R)-5-hydroxy-6-(hydroxymethyl)oxan-2-yl]pyrimidin-2-one
Synonym More Synonyms

  Biological Activity

Description 1-(2,3-Dideoxy-β-D-erythro-hexo pyranosyl)cytosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Density 1.63g/cm3
Boiling Point 491.8ºC at 760mmHg
Molecular Formula C10H15N3O5
Molecular Weight 257.24
Flash Point 251.3ºC
Exact Mass 241.10600
PSA 111.59000
Vapour Pressure 9.77E-12mmHg at 25°C
Index of Refraction 1.691

 Synthetic Route

N/A structure

N/A

CAS#:145593-86-8

~84%

1-(2,3-Dideoxy-β-D-erythro-hexo pyranosyl)cytosine Structure

1-(2,3-Dideoxy-...

CAS#:136020-18-3

Literature: Boehringer, Markus; Roth, Hans-Joerg; Hunziker, Juerg; Goebel, Michael; Krishnan, Ravichandran; et al. Helvetica Chimica Acta, 1992 , vol. 75, # 5 p. 1416 - 1477
N4-Benzoyl-1-(4',6'-di-O-acetyl-2',3'-dideoxy-β-D-glucopyranosyl)cytosin structure

N4-Benzoyl-1-(4...

CAS#:145593-78-8

~%

1-(2,3-Dideoxy-β-D-erythro-hexo pyranosyl)cytosine Structure

1-(2,3-Dideoxy-...

CAS#:136020-18-3

Literature: Boehringer, Markus; Roth, Hans-Joerg; Hunziker, Juerg; Goebel, Michael; Krishnan, Ravichandran; et al. Helvetica Chimica Acta, 1992 , vol. 75, # 5 p. 1416 - 1477

 Synonyms

2',3'-Dideoxy-hexopyranosyl cytidine
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Chemsrc provides CAS#:136020-18-3 MSDS, density, melting point, boiling point, structure, etc. Its name is 1-(2,3-Dideoxy-β-D-erythro-hexo pyranosyl)cytosine>> amp version: 1-(2,3-Dideoxy-β-D-erythro-hexo pyranosyl)cytosine

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