(5E)-5-(dimethylaminohydrazinylidene)imidazole-4-carboxamide,hydrochloride

Modify Date: 2024-02-26 11:39:10

(5E)-5-(dimethylaminohydrazinylidene)imidazole-4-carboxamide,hydrochloride Structure
(5E)-5-(dimethylaminohydrazinylidene)imidazole-4-carboxamide,hydrochloride structure
Common Name (5E)-5-(dimethylaminohydrazinylidene)imidazole-4-carboxamide,hydrochloride
CAS Number 17925-90-5 Molecular Weight 218.64400
Density N/A Boiling Point 302.6ºC at 760 mmHg
Molecular Formula C6H11ClN6O Melting Point N/A
MSDS N/A Flash Point 136.8ºC

 Use of (5E)-5-(dimethylaminohydrazinylidene)imidazole-4-carboxamide,hydrochloride


Dacarbazine hydrochloride is a cell cycle nonspecific antineoplastic alkylating agent. Dacarbazine hydrochloride inhibits T and B lymphoblastic response, with IC50 values of 50 and 10 μg/mL, respectively. Dacarbazine hydrochloride can be used for the research of metastatic malignant melanoma[1][2].

 Names

Name (5E)-5-(dimethylaminohydrazinylidene)imidazole-4-carboxamide,hydrochloride
Synonym More Synonyms

  Biological Activity

Description Dacarbazine hydrochloride is a cell cycle nonspecific antineoplastic alkylating agent. Dacarbazine hydrochloride inhibits T and B lymphoblastic response, with IC50 values of 50 and 10 μg/mL, respectively. Dacarbazine hydrochloride can be used for the research of metastatic malignant melanoma[1][2].
Related Catalog
References

[1]. Rojo JM, et al. Inhibition of T and B lymphoblastic response by mithramycin, dacarbazine, prospidium chloride and peptichemio. Chemotherapy. 1983;29(5):345-51.

[2]. Al-Badr AA, et al. Dacarbazine. Profiles Drug Subst Excip Relat Methodol. 2016;41:323-77.

 Chemical & Physical Properties

Boiling Point 302.6ºC at 760 mmHg
Molecular Formula C6H11ClN6O
Molecular Weight 218.64400
Flash Point 136.8ºC
Exact Mass 218.06800
PSA 95.44000
Vapour Pressure 0.000981mmHg at 25°C

 Synonyms

5-(3,3-Dimethyl-1-triazeno)-1H-imidazole-4-carboxamide monohydrochloride
Imidazole-4-carboxamide,5-(3,3-dimethyl-1-triazeno)-,monohydrochloride
Dacarbazine HCl
Dacarbazine hydrochloride