MPO-IN-4

Modify Date: 2024-01-16 11:16:22

MPO-IN-4 Structure
MPO-IN-4 structure
Common Name MPO-IN-4
CAS Number 2088545-68-8 Molecular Weight 225.25
Density N/A Boiling Point N/A
Molecular Formula C12H11N5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of MPO-IN-4


MPO-IN-4 (compound 12) is a potent and selective myeloperoxidase (MPO) inhibitor with an IC500 of 25 nM. MPO-IN-4 has no effect on methyl guanine methyl transferase (MGMT)[1].

 Names

Name MPO-IN-4

 MPO-IN-4 Biological Activity

Description MPO-IN-4 (compound 12) is a potent and selective myeloperoxidase (MPO) inhibitor with an IC500 of 25 nM. MPO-IN-4 has no effect on methyl guanine methyl transferase (MGMT)[1].
Related Catalog
References

[1]. Scott A Shaw, et al. Discovery and structure activity relationships of 7-benzyl triazolopyridines as stable, selective, and reversible inhibitors of myeloperoxidase. Bioorg Med Chem. 2020 Nov 15;28(22):115723.

 Chemical & Physical Properties

Molecular Formula C12H11N5
Molecular Weight 225.25