Thiabendazole-13C6

Modify Date: 2024-04-06 19:07:50

Thiabendazole-13C6 structure	Common Name	Thiabendazole-13C6
	CAS Number	2140327-29-1	Molecular Weight	207.20
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₄₁₃C₆H₇N₃S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Thiabendazole-13C6

Thiabendazole-13C6 is the 13C6 labeled Thiabendazole. Thiabendazole inhibites the mitochondrial helminth-specific enzyme, fumarate reductase, with anthelminthic property.

Name	Thiabendazole-13C6

Description	Thiabendazole-13C6 is the 13C6 labeled Thiabendazole. Thiabendazole inhibites the mitochondrial helminth-specific enzyme, fumarate reductase, with anthelminthic property.
Related Catalog	Research Areas >> Infection
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-223. [2]. Cha, H.J., et al., Evolutionarily repurposed networks reveal the well-known antifungal drug thiabendazole to be a novel vascular disrupting agent. PLoS Biol, 2012. 10(8): p. e1001379. [3]. Zhang, J., et al., Thiabendazole, a well-known antifungal drug, exhibits anti-metastatic melanoma B16F10 activity via inhibiting VEGF expression and inducing apoptosis. Pharmazie, 2013. 68(12): p. 962-8.

Molecular Formula	C₄₁₃C₆H₇N₃S
Molecular Weight	207.20