ALK5-IN-31 structure
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Common Name | ALK5-IN-31 | ||
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CAS Number | 2785430-87-5 | Molecular Weight | 430.48 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C23H23FN8 | Melting Point | N/A | |
MSDS | N/A | Flash Point | N/A |
Use of ALK5-IN-31ALK5-IN-31 (compound Ex-08) is a selective ALK-5 inhibitor (IC50≤10 nM), inhibits TGF-β-induced SMAD signaling. ALK5-IN-31 has the potential to inhibit growth of tumour in vivo. ALK5-IN-31 can be used in study of proliferative diseases such as cancer, fibrotic diseases, and systemic sclerosis[1]. |
Name | ALK5-IN-31 |
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Description | ALK5-IN-31 (compound Ex-08) is a selective ALK-5 inhibitor (IC50≤10 nM), inhibits TGF-β-induced SMAD signaling. ALK5-IN-31 has the potential to inhibit growth of tumour in vivo. ALK5-IN-31 can be used in study of proliferative diseases such as cancer, fibrotic diseases, and systemic sclerosis[1]. |
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Related Catalog | |
Target |
ALK-5[1]. |
References |
[1]. Bettina FRANZ, et al. Alk-5 inhibitors and uses thereof. Patent WO2022126133A1. |
Molecular Formula | C23H23FN8 |
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Molecular Weight | 430.48 |