(2,2,9,9-2H4)Decanedioic acid

Modify Date: 2024-01-20 18:32:19

(2,2,9,9-2H4)Decanedioic acid Structure
(2,2,9,9-2H4)Decanedioic acid structure
Common Name (2,2,9,9-2H4)Decanedioic acid
CAS Number 339080-77-2 Molecular Weight 206.272
Density 1.1±0.1 g/cm3 Boiling Point 374.3±0.0 °C at 760 mmHg
Molecular Formula C10H14D4O4 Melting Point N/A
MSDS N/A Flash Point 198.3±19.7 °C

 Use of (2,2,9,9-2H4)Decanedioic acid


Decanedioic acid-d4 is the deuterium labeled Decanedioic acid[1]. Decanedioic acid, a normal urinary acid, is found to be associated with carnitine-acylcarnitine translocase deficiency and medium chain acyl-CoA dehydrogenase deficiency[2].

 Names

Name 1,10-decanedioic-2,2,9,9-d4 acid
Synonym More Synonyms

 (2,2,9,9-2H4)Decanedioic acid Biological Activity

Description Decanedioic acid-d4 is the deuterium labeled Decanedioic acid[1]. Decanedioic acid, a normal urinary acid, is found to be associated with carnitine-acylcarnitine translocase deficiency and medium chain acyl-CoA dehydrogenase deficiency[2].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

[2]. Bertuzzi A, et al. Sebacic acid binding to human plasma albumin. Biochem Pharmacol. 1993 Feb 9;45(3):697-702.  

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 374.3±0.0 °C at 760 mmHg
Molecular Formula C10H14D4O4
Molecular Weight 206.272
Flash Point 198.3±19.7 °C
Exact Mass 206.145615
PSA 74.60000
LogP 1.86
Vapour Pressure 0.0±1.8 mmHg at 25°C
Index of Refraction 1.475

 Synonyms

(2,2,9,9-H)Decanedioic acid
Decanedioic-2,2,9,9-d acid