Sodium 3-hydroxy(2,2-2H2)butanoate

Modify Date: 2024-01-06 20:09:45

Sodium 3-hydroxy(2,2-2H2)butanoate Structure
Sodium 3-hydroxy(2,2-2H2)butanoate structure
Common Name Sodium 3-hydroxy(2,2-2H2)butanoate
CAS Number 352439-00-0 Molecular Weight 128.099
Density N/A Boiling Point N/A
Molecular Formula C4H5D2NaO3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Sodium 3-hydroxy(2,2-2H2)butanoate


3-Hydroxybutyric acid-d2 (sodium) is the deuterium labeled 3-Hydroxybutyric acid sodium[1]. 3-Hydroxybutyric acid sodium (β-Hydroxybutyric acid sodium) is a metabolite that is elevated in type I diabetes. 3-Hydroxybutyric acid sodium can modulate the properties of membrane lipids[2].

 Names

Name sodium 3-hydroxybutyrate-2,2-d2
Synonym More Synonyms

 Sodium 3-hydroxy(2,2-2H2)butanoate Biological Activity

Description 3-Hydroxybutyric acid-d2 (sodium) is the deuterium labeled 3-Hydroxybutyric acid sodium[1]. 3-Hydroxybutyric acid sodium (β-Hydroxybutyric acid sodium) is a metabolite that is elevated in type I diabetes. 3-Hydroxybutyric acid sodium can modulate the properties of membrane lipids[2].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

[2]. Hsu TT, et al. 3-Hydroxybutyric acid interacts with lipid monolayers at concentrations that impair consciousness. Langmuir. 2013 Feb 12;29(6):1948-55.  

 Chemical & Physical Properties

Molecular Formula C4H5D2NaO3
Molecular Weight 128.099
Exact Mass 128.041840
PSA 60.36000

 Synonyms

sodium dl-3-hydroxybutyrate-2,2-d2
Sodium 3-hydroxy(2,2-H)butanoate
Butanoic-2,2-d acid, 3-hydroxy-, sodium salt (1:1)