2'-Deoxyuridine-15N2

Modify Date: 2024-01-31 18:21:30

2'-Deoxyuridine-15N2 Structure
2'-Deoxyuridine-15N2 structure
Common Name 2'-Deoxyuridine-15N2
CAS Number 494754-69-7 Molecular Weight 230.19
Density N/A Boiling Point N/A
Molecular Formula C9H1215N2O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 2'-Deoxyuridine-15N2


2'-Deoxyuridine-15N2 is the 15N labeled 2'-Deoxyuridine. 2'-Deoxyuridine could increase chromosome breakage and results in a decreased thymidylate synthetase activity. A known use of 2'-Deoxyuridine is as a precursor in the synthesis of Edoxud[1]

 Names

Name 2'-Deoxyuridine-15N2

 2'-Deoxyuridine-15N2 Biological Activity

Description 2'-Deoxyuridine-15N2 is the 15N labeled 2'-Deoxyuridine. 2'-Deoxyuridine could increase chromosome breakage and results in a decreased thymidylate synthetase activity. A known use of 2'-Deoxyuridine is as a precursor in the synthesis of Edoxud[1]
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.

[2]. Reidy JA, et al. Deoxyuridine increases folate-sensitive fragile site expression in human lymphocytes. Am J Med Genet. 1987 Jan;26(1):1-5.

 Chemical & Physical Properties

Molecular Formula C9H1215N2O5
Molecular Weight 230.19