3-chloro-N-[[1-(1H-indol-3-ylmethyl)-6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl]methyl]aniline

Modify Date: 2024-02-29 17:55:47

3-chloro-N-[[1-(1H-indol-3-ylmethyl)-6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl]methyl]aniline structure	Common Name	3-chloro-N-[[1-(1H-indol-3-ylmethyl)-6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl]methyl]aniline
	CAS Number	84218-38-2	Molecular Weight	461.98300
	Density	1.272g/cm3	Boiling Point	665ºC at 760 mmHg
	Molecular Formula	C₂₇H₂₈ClN₃O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	356ºC

Name	3-chloro-N-[[1-(1H-indol-3-ylmethyl)-6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl]methyl]aniline

Density	1.272g/cm3
Boiling Point	665ºC at 760 mmHg
Molecular Formula	C₂₇H₂₈ClN₃O₂
Molecular Weight	461.98300
Flash Point	356ºC
Exact Mass	461.18700
PSA	49.52000
LogP	6.06090
Index of Refraction	1.669

CHEMICAL IDENTIFICATION

RTECS NUMBER :: NX4919200

CHEMICAL NAME :: Isoquinoline, 1,2,3,4-tetrahydro-2-((m-chloroanilino)methyl)-6,7-di methoxy-1- (3-indolylmethyl)-

CAS REGISTRY NUMBER :: 84218-38-2

LAST UPDATED :: 198609

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C27-H28-Cl-N3-O2

MOLECULAR WEIGHT :: 462.03

WISWESSER LINE NOTATION :: T66 CNT&J C1MR CG& HO1 IO1 B1- DT56 BMJ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 750 mg/kg

TOXIC EFFECTS :: Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - proteases Biochemical - Metabolism (Intermediary) - effect on inflammation or mediation of inflammation

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 32,1233,1982