3',4'-DICHLOROBENZAMIL HYDROCHLORIDE
3',4'-DICHLOROBENZAMIL HYDROCHLORIDE structure
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Common Name | 3',4'-DICHLOROBENZAMIL HYDROCHLORIDE | ||
|---|---|---|---|---|
| CAS Number | 928621-15-2 | Molecular Weight | 425.1 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C13H13Cl4N7O | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | N/A | |
| Symbol |
GHS07 |
Signal Word | Warning | |
| Name | 3',4'-DICHLOROBENZAMIL HYDROCHLORIDE |
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| Molecular Formula | C13H13Cl4N7O |
|---|---|
| Molecular Weight | 425.1 |
| Appearance of Characters | solid |
| Storage condition | 2-8°C |
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Amiloride derivatives are potent blockers of KATP channels.
Naunyn Schmiedebergs Arch. Pharmacol. 364(4) , 351-8, (2001) In cardiomyocytes sarcolemmal KATP channels open massively when the cytosolic [ATP] drops into the range of tens of micromolar, as during acute ischemia. The diuretic drug amiloride and related deriva... |
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Modulation of neuroprotective effect of ischemic post-conditioning by dichlorobenzamil a Na(+)/Ca(2+) exchanger inhibitor in mice.
Biol. Pharm. Bull. 33(4) , 585-91, (2010) The present study has been designed to investigate the modulatory role of dichlorobenzamil a Na(+)/Ca(2+) exchanger inhibitor in ischemic post-conditioning-induced neuroprotection in mice. Bilateral c... |
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Stimulation of large-conductance Ca2+-activated K+ channels by the Na+/Ca2+ exchanger inhibitor dichlorobenzamil in cultured human umbilical vein endothelial cells and mouse aortic smooth muscle cells.
J. Physiol. Pharmacol. 60(1) , 43-50, (2009) We investigated the effects of the selective inhibitor of Na(+)/Ca(2+) exchanger (NCX), 2',4'- and 3',4'-dichlorobenzamil (DCB), on large-conductance Ca(2+)-activated K(+) (BK(Ca)) channels in culture... |