4H-Pyran-4-one,2,6-bis(4-methoxyphenyl)-

更新时间：2024-01-09 01:09:21

4H-Pyran-4-one,2,6-bis(4-methoxyphenyl)-结构式	常用名	4H-Pyran-4-one,2,6-bis(4-methoxyphenyl)-	英文名	4H-Pyran-4-one,2,6-bis(4-methoxyphenyl)-
	CAS号	1678-14-4	分子量	308.32800
	密度	1.218g/cm3	沸点	528.3ºC at 760mmHg
	分子式	C₁₉H₁₆O₄	熔点	N/A
	MSDS	N/A	闪点	235.1ºC

用途

NSC81111是一种有效的口服EGFR-TK抑制剂,IC50为0.15 nM。NSC81111具有抗癌作用[1]。

英文名	2,6-bis(4-methoxyphenyl)pyran-4-one
英文别名	更多

描述	NSC81111是一种有效的口服EGFR-TK抑制剂,IC50为0.15 nM。NSC81111具有抗癌作用[1]。
相关类别	研究领域 >> 癌症信号通路 >> JAK/STAT信号通路 >> EGFR 信号通路 >> 蛋白酪氨酸激酶 >> EGFR
靶点	IC50: 0.15 nM (EGFR-TK)[1]
参考文献	[1]. Nattanan Jiwacharoenchai, et al. Discovery of potent antiproliferative agents from selected oxygen heterocycles as EGFR tyrosine kinase inhibitors from the U.S. National Cancer Institute database by in silico screening and bioactivity evaluation. Bioorg Med Chem Lett. 2022 Feb 15;58:128524.

密度	1.218g/cm3
沸点	528.3ºC at 760mmHg
分子式	C₁₉H₁₆O₄
分子量	308.32800
闪点	235.1ºC
精确质量	308.10500
PSA	48.67000
LogP	3.99100
蒸汽压	3.01E-11mmHg at 25°C
折射率	1.597

1,3,5-Pentanetr...

1469-93-8

~84%

4H-Pyran-4-one,...

1678-14-4

文献：Knight, John D.; Metz, Clyde R.; Beam, Charles F.; Pennington, William T.; VanDerveer, Donald G. Synthetic Communications, 2008 , vol. 38, # 14 p. 2465 - 2482

1-(4-methoxyphe...

55991-65-6

5-(4-methoxyphe...

55991-69-0

~21%

4H-Pyran-4-one,...

1678-14-4

文献：Saitoh; Oyama; Sakurai; Niimura; Hinata; Horiguchi; Toda; Sano Chemical and Pharmaceutical Bulletin, 1996 , vol. 44, # 5 p. 956 - 966

对甲氧基苯乙酮

100-06-1

4H-Pyran-4-one,...

1678-14-4

文献：Saitoh; Oyama; Sakurai; Niimura; Hinata; Horiguchi; Toda; Sano Chemical and Pharmaceutical Bulletin, 1996 , vol. 44, # 5 p. 956 - 966

1-(4-methoxyphe...

55991-65-6

4H-Pyran-4-one,...

1678-14-4

文献：Saitoh; Oyama; Sakurai; Niimura; Hinata; Horiguchi; Toda; Sano Chemical and Pharmaceutical Bulletin, 1996 , vol. 44, # 5 p. 956 - 966

ETHYL 3-(4-METH...

51718-85-5

4H-Pyran-4-one,...

1678-14-4

文献：El-Kholy et al. Journal of the Chemical Society, 1959 , p. 2588,2591

4H-Pyran-4-one,2,6-bis(4-methoxyphenyl)-上游产品 5
CAS号1469-93-8 1,3,5-Pentanetr... CAS号55991-65-6 1-(4-methoxyphe... CAS号55991-69-0 5-(4-methoxyphe... CAS号100-06-1 对甲氧基苯乙酮
CAS号51718-85-5 ETHYL 3-(4-METH...
4H-Pyran-4-one,2,6-bis(4-methoxyphenyl)-下游产品 2
CAS号100-09-4 对甲氧基苯甲酸 CAS号100-06-1 对甲氧基苯乙酮

2,6-bis-(4-methoxy-phenyl)-pyran-4-one

4H-Pyran-4-one,2,6-bis(p-methoxyphenyl)

2,6-bis(4-methoxyphenyl)-4H-pyran-4-one

2.6-Bis-<4-methoxy-phenyl>-4-pyron

2,6-Bis-(4-methoxy-phenyl)-pyran-4-on

2,6-di-(4-methoxyphenyl)-4H-pyran-4-one

2.6-Di-<4-methoxy-phenyl>-4-pyron

4H-Pyran-4-one,2,6-bis(4-methoxyphenyl)-

用途

4H-Pyran-4-one,2,6-bis(4-methoxyphenyl)-名称

4H-Pyran-4-one,2,6-bis(4-methoxyphenyl)-生物活性

4H-Pyran-4-one,2,6-bis(4-methoxyphenyl)-物理化学性质

4H-Pyran-4-one,2,6-bis(4-methoxyphenyl)-合成线路

4H-Pyran-4-one,2,6-bis(4-methoxyphenyl)-上下游产品

4H-Pyran-4-one,2,6-bis(4-methoxyphenyl)-英文别名