α-己基肉桂醛

α-己基肉桂醛用途

【用途一】
日用
【用途二】
萃取溶剂。主要用于大豆、米糠、棉籽等各种食用油脂和香辛料中油树脂等的抽提。
GB 2760-96规定为食品加工助剂。
【用途三】
α-己基肉桂醛是我国《食品添加剂使用卫生标准》规定允许使用的食品香料，主要用于配制蜂蜜、水果型食用香精和混合型香料。在糖果中使用量为6.5mg/kg；冷饮中2.6mg/kg；烘烤食品中2.4mg/kg；软饮料中0.8mg/kg；布丁类中0.05mg/kg。
【用途四】
是配制树兰花油的很好原料。是合成香料中最富有花香的品种之一。又带有愉快的油青气息，与易挥发的花香香料共用，可使之更生动。可用于茉莉、玉兰等花香香精，也可用于其他香型中。还可微量用于食用香精，如蜜香和各种果香型香精。
【用途五】
GB 2760--2001规定为允许使用的食品用香料。主要用以配制蜂蜜和水果型香精及混合香辛料。
【用途六】
该品有茉莉香味，经a-戊基肉桂醛和香味更浓、更稳定。用于肥皂、洗涤剂中。

α-己基肉桂醛名称

[ CAS 号 ]:
101-86-0

[ 中文名 ]:
α-己基肉桂醛

[ 英文名 ]:
Hexyl cinnamaldehyde

[中文别名 ]:

甲位己基桂醛

[英文别名 ]:

EINECS 202-983-3
2-Hexyl-3-phenyl-2-propenal
Octanal, 2-(phenylmethylene)-, (2E)-
α-hexyl cinnamaldehyde
JASMONAL H
α-Hexylcinnamic aldehyde
MFCD00006989
(2E)-2-Benzylideneoctanal
α-Hexylcinnamaldehyde
2-hexyl-3-phenylpropenal

α-己基肉桂醛生物活性

[ 描述 ]:

α-己基肉桂醛,一种从肉桂醛衍生而来的化合物。α-己基肉桂醛具有潜在的抗突变和化学增敏特性。α-己基肉桂醛广泛用作许多个人护理品的成分,以及食品和制药工业的添加剂[1]。

[ 相关类别 ]:

研究领域 >> 癌症

信号通路 >> 其他 >> 其他

[参考文献]

[1]. Maria Grazia Sarpietro, et al. Interaction of α-Hexylcinnamaldehyde with a Biomembrane Model: A Possible MDR Reversal Mechanism. J Nat Prod. 2015 May 22;78(5):1154-9.

α-己基肉桂醛物理化学性质

[ 密度 ]:
1.0±0.1 g/cm3

[ 沸点 ]:
308.1±0.0 °C at 760 mmHg

[ 分子式 ]:
C₁₅H₂₀O

[ 分子量 ]:
216.319

[ 闪点 ]:
140.5±14.6 °C

[ 精确质量 ]:
216.151413

[ PSA ]:
17.07000

[ LogP ]:
5.33

[ 外观性状 ]:
无色到黄色液体

[ 蒸汽压 ]:
0.0±0.6 mmHg at 25°C

[ 折射率 ]:
1.530

[ 储存条件 ]:
2-8°C

α-己基肉桂醛MSDS

详细MSDS(安全技术说明书)

α-己基肉桂醛毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: GD6560000

CHEMICAL NAME :: Cinnamaldehyde, alpha-hexyl-

CAS REGISTRY NUMBER :: 101-86-0

LAST UPDATED :: 199710

DATA ITEMS CITED :: 9

MOLECULAR FORMULA :: C15-H20-O

MOLECULAR WEIGHT :: 216.35

WISWESSER LINE NOTATION :: VHY6&U1R

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 12,915,1974

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: CTOIDG Cosmetics and Toiletries. (Allured Pub. Corp., POB 318, Wheaton, IL 60189) V.91- 1976- Volume(issue)/page/year: 94(8),41,1979

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - guinea pig

REFERENCE :: CTOIDG Cosmetics and Toiletries. (Allured Pub. Corp., POB 318, Wheaton, IL 60189) V.91- 1976- Volume(issue)/page/year: 94(8),41,1979 ** ACUTE TOXICITY DATA **

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 3100 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 12,915,1974

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2300 mg/kg

TOXIC EFFECTS :: Sense Organs and Special Senses (Olfaction) - effect, not otherwise specified Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - dyspnea

REFERENCE :: GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 55(6),86,1990 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X6658 No. of Facilities: 2796 (estimated) No. of Industries: 11 No. of Occupations: 19 No. of Employees: 46014 (estimated) No. of Female Employees: 25863 (estimated)

α-己基肉桂醛安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H317

[ 警示性声明 ]:
P280

[ 个人防护装备 ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ 危害码 (欧洲) ]:
C:Corrosive

[ 风险声明 (欧洲) ]:
R34

[ 安全声明 (欧洲) ]:
S26-S36/37/39-S45-S36

[ 危险品运输编码 ]:
UN 3265 8/PG 3

[ WGK德国 ]:
2

[ RTECS号 ]:
GD6560000

[ 海关编码 ]:
2912299000

α-己基肉桂醛合成路线

详细合成路线

α-己基肉桂醛上下游产品

α-己基肉桂醛上游产品

α-己基肉桂醛下游产品

α-己基肉桂醛制备

1.由石油分馏所得汽油经接触改质装置得改质油，经脱硫并分馏除去苯等芳香族碳氢化物后再精制而成。由苯甲醛和正辛醛在碱存在下缩合而得。

2.由苯甲醛与正辛醛在碱存在下缩合制得。

α-己基肉桂醛海关

[ 海关编码 ]: 2912299000

[ 中文概述 ]:
2912299000. 其他不含其他含氧基的环醛. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:5.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 四聚甲醛报明外观

[ Summary ]:
2912299000. other cyclic aldehydes without other oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0%

α-己基肉桂醛文献

Natural ingredients based cosmetics. Content of selected fragrance sensitizers.

Contact Dermatitis 34(6) , 423-6, (1996)

In the present study, we have investigated 42 cosmetic products based on natural ingredients for content of 11 fragrance substances: geraniol, hydroxycitronellal, eugenol, isoeugenol, cinnamic aldehyd...

Evaluation of an ex vivo murine local lymph node assay: multiple endpoint comparison.

J. Appl. Toxicol. 26(4) , 333-40, (2006)

The local lymph node assay (LLNA) is used to assess the skin sensitization potential of chemicals. In the standard assay, mice are treated topically on the dorsum of both ears with test substance for ...

Patch testing with a new fragrance mix detects additional patients sensitive to perfumes and missed by the current fragrance mix.

Contact Dermatitis 52(4) , 207-15, (2005)

The currently used 8% fragrance mix (FM I) does not identify all patients with a positive history of adverse reactions to fragrances. A new FM II with 6 frequently used chemicals was evaluated in 1701...

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