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1-哌啶丙醇

1-哌啶丙醇用途

用于有机合成。

1-哌啶丙醇名称

[ CAS 号 ]:
104-58-5

[ 中文名 ]:
1-哌啶丙醇

[ 英文名 ]:
1-Piperidinepropanol

[英文别名 ]:

3-Piperidino-1-propanol
3-piperidin-1-ylpropan-1-ol
3-(1-Piperidino)propanol
Piperidine-1-propanol
1-Propanol, 3-piperidino-
1-Piperidinepropanol
3-(piperidin-1-yl)propan-1-ol
3-(1-Piperidinyl)-1-propanol
MFCD00023781
EINECS 203-216-5

1-哌啶丙醇物理化学性质

[ 密度 ]:
1.0±0.1 g/cm3

[ 沸点 ]:
237.9±23.0 °C at 760 mmHg

[ 分子式 ]:
C₈H₁₇NO

[ 分子量 ]:
143.227

[ 闪点 ]:
105.6±21.3 °C

[ 精确质量 ]:
143.131012

[ PSA ]:
23.47000

[ LogP ]:
0.46

[ 外观性状 ]:
液体;Colorless to Light yellow clear liquid

[ 蒸汽压 ]:
0.0±1.0 mmHg at 25°C

[ 折射率 ]:
1.477

[ 储存条件 ]:
存放于惰性气体之中;避免空气

1-哌啶丙醇MSDS

详细MSDS(安全技术说明书)

1-哌啶丙醇毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TN2414500

CHEMICAL NAME :: 1-Piperidinepropanol

CAS REGISTRY NUMBER :: 104-58-5

BEILSTEIN REFERENCE NO. :: 0001275

LAST UPDATED :: 199612

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C8-H17-N-O

MOLECULAR WEIGHT :: 143.26

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 58 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PHARAT Pharmazie. (VEB Verlag Volk und Gesundheit, Neue Gruenstr. 18, Berlin DDR-1020, Ger. Dem. Rep.) V.1- 1946- Volume(issue)/page/year: 14,201,1959 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X7918 No. of Facilities: 4 (estimated) No. of Industries: 1 No. of Occupations: 16 No. of Employees: 1440 (estimated)

1-哌啶丙醇安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H315-H319-H335

[ 警示性声明 ]:
P261-P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xi: Irritant;

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
S26-S36

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ RTECS号 ]:
TN2414500

[ 海关编码 ]:
2933399090

1-哌啶丙醇合成路线

详细合成路线

1-哌啶丙醇上下游产品

1-哌啶丙醇上游产品

1-哌啶丙醇下游产品

1-哌啶丙醇海关

[ 海关编码 ]: 2933399090

[ 中文概述 ]:
2933399090. 其他结构含非稠合吡啶环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

1-哌啶丙醇文献

Synthesis and evaluation of N-alkyl-S-[3-(piperidin-1-yl)propyl]isothioureas: High affinity and human/rat species-selective histamine H3 receptor antagonists

Bioorg. Med. Chem. Lett. 23(23) , 6415-20, (2013)

OUP-186: histamine H3R antagonist inactive in rats, but especially potent in humans.

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