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L-天冬氨酸钾

L-天冬氨酸钾用途

天冬氨酸钾是一种氨基酸,可用作结肠定位药物递送的合适前药[1][2]。

L-天冬氨酸钾名称

[ CAS 号 ]:
1115-63-5

[ 中文名 ]:
L-天冬氨酸钾盐

[ 英文名 ]:
Butanedioate, 2-amino-, potassium salt (1:1)

[中文别名 ]:

[英文别名 ]:

L-Aspartic acid 1-potassium salt
L-Asparaginic Acid Potassium Salt Hydrate
Potassium L-aspartate
potassiumhydrogenaspartate
L-Aspartate Potassium
L-ASPARTIC ACID POTTASIUM SALT
potassium aspartate
L-Aspartic Acid Potassium Salt Hydrate
L-Aspartic acid potassium salt dihydrate
L-ASPARTIC ACID MONOPOTASSIUM

L-天冬氨酸钾生物活性

[ 描述 ]:

天冬氨酸钾是一种氨基酸,可用作结肠定位药物递送的合适前药[1][2]。

[ 相关类别 ]:

研究领域 >> 心血管疾病

[ 靶点 ]

Microbial Metabolite

Human Endogenous Metabolite

[参考文献]

[1]. Hosoya K, et al. Blood-brain barrier produces significant efflux of L-aspartic acid but not D-aspartic acid: in vivo evidence using the brain efflux index method. J Neurochem. 1999 Sep;73(3):1206-11.

[2]. Leopold CS, et al. In vivo pharmacokinetic study for the assessment of poly(L-aspartic acid) as a drug carrier for colon-specific drug delivery. J Pharmacokinet Biopharm. 1995 Aug;23(4):397-406.

L-天冬氨酸钾物理化学性质

[ 熔点 ]:
270-271ºC

[ 分子式 ]:
C₄H₆KNO₄

[ 分子量 ]:
170.186

[ 精确质量 ]:
169.986115

[ PSA ]:
103.45000

[ 外观性状 ]:
固体;White to Almost white powder to crystal

[ 折射率 ]:
20.5 ° (C=8, 6mol/L HCl)

[ 储存条件 ]:
Store desiccated in air-tight containers.

L-天冬氨酸钾MSDS

L-天冬氨酸钾安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危害码 (欧洲) ]:
Xi

[ 安全声明 (欧洲) ]:
24/25

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ RTECS号 ]:
CI9458500

[ 海关编码 ]:
2922509090

L-天冬氨酸钾合成路线

L-天冬氨酸钾上下游产品

L-天冬氨酸钾上游产品

L-天冬氨酸钾下游产品

L-天冬氨酸钾海关

[ 海关编码 ]: 2922509090

[ 中文概述 ]:
2922509090. 其他氨基醇酚、氨基酸酚及其他含氧基氨基化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件：AB. 最惠国关税:6.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乙醇胺及其盐应报明色度, 乙醇胺及其盐应报明包装

[ 监管条件 ]: A.入境货物通关单 B.出境货物通关单

[ 检验检疫 ]: R.进口食品卫生监督检验 S.出口食品卫生监督检验

[ Summary ]:
2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

L-天冬氨酸钾文献

8DSS-promoted remineralization of initial enamel caries in vitro.

J. Dent. Res. 93(5) , 520-4, (2014)

Peptides containing 8 repeats of aspartate-serine-serine (8DSS) have been shown to promote the nucleation of calcium phosphate from solution into human enamel. Here we tested the ability of 8DSS to pr...

Fluoride exposure regulates the elongation phase of protein synthesis in cultured Bergmann glia cells.

Toxicol. Lett. 229(1) , 126-33, (2014)

Fluoride is an environmental pollutant present in dental products, food, pesticides and water. The latter, is the greatest source of exposure to this contaminant. Structural and functional damages to ...

Low resolution X-ray structure of γ-glutamyltranspeptidase from Bacillus licheniformis: opened active site cleft and a cluster of acid residues potentially involved in the recognition of a metal ion.

Biochim. Biophys. Acta 1844(9) , 1523-9, (2014)

γ-Glutamyltranspeptidases (γ-GTs) cleave the γ-glutamyl amide bond of glutathione and transfer the released γ-glutamyl group to water (hydrolysis) or acceptor amino acids (transpeptidation). These ubi...

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