L-半胱氨酰-L-ALPHA-天冬氨酰-L-脯氨酰甘氨酰-L-酪氨酰-L-异亮氨酰甘氨酰-L-丝氨酰-N5-(二氨基亚甲基)-L-鸟氨酸

用途

PA22-2 (free acid) (Cys-Laminin A chain 2091-2108) 是一种支持神经突生长并刺激神经元样过程形成的多肽。PA22-2 (free acid) 可用于培养人腺样囊性癌细胞,并用于制备肽功能化支撑磷脂双层< sup>[3]。

名称

[ CAS 号 ]:
123063-31-0

[ 中文名 ]:
L-半胱氨酰-L-ALPHA-天冬氨酰-L-脯氨酰甘氨酰-L-酪氨酰-L-异亮氨酰甘氨酰-L-丝氨酰-N5-(二氨基亚甲基)-L-鸟氨酸

[ 英文名 ]:
H-Cys-Ser-Arg-Ala-Arg-Lys-Gln-Ala-Ala-Ser-Ile-Lys-Val-Ala-Val-Ser-Ala-Asp-Arg-OH trifluoroacetate salt

[英文别名 ]:

生物活性

[ 描述 ]:

[ 相关类别 ]:

研究领域 >> 其他

信号通路 >> 其他 >> 其他

[参考文献]

[1]. Yung-Chih Kuo, et al. Inverted colloidal crystal scaffolds with induced pluripotent stem cells for nerve tissue engineering. Colloids Surf B Biointerfaces. 2013 Feb 1:102:789-94.

[2]. D Thid, et al. Supported phospholipid bilayers as a platform for neural progenitor cell culture.J Biomed Mater Res A. 2008 Mar 15;84(4):940-53.

[3]. Ahu Arslan Yildiz, et al. Cell-free synthesis of cytochrome bo(3) ubiquinol oxidase in artificial membranes. Anal Biochem. 2012 Apr 1;423(1):39-45.

物理化学性质

[ 分子式 ]:
C₈₂H₁₄₉N₃₁O₂₆S

[ 分子量 ]:
2017.32000

[ 精确质量 ]:
2016.10000

[ PSA ]:
1004.74000

[ 外观性状 ]:
固体

[ 储存条件 ]:
20°C

MSDS

详细MSDS(安全技术说明书)

安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危险品运输编码 ]:
NONH for all modes of transport

文献

Laminin A chain synthetic peptide which supports neurite outgrowth.

Biochem. Biophys. Res. Commun. 162 , 821, (1989)

Neurons from peripheral and central nervous tissue as well as from established cell lines respond to low concentrations of laminin with rapid extension of axon-like processes. Two sites on laminin hav...

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