保泰松钠
保泰松钠用途
解热镇痛药,用于治疗风湿性和类风湿性关节炎及痛风等
保泰松钠名称
[ CAS 号 ]:
129-18-0
[ 中文名 ]:
保泰松钠
[ 英文名 ]:
phenylbutazone sodium
[中文别名 ]:
[英文别名 ]:
- PHENYLBUTAZONE SODIUM
- 3,5-dioxo-1,2-diphenyl-4-n-butylpyrazolidinsodium
- 4-BUTYL-1,2-DIPHENYL-3,5-PYRAZOLIDINEDIONE SODIUM
- Einecs 204-935-7
- diphenyldioxobutylpyrazolidine-butazolidine-sodium
- Phenylbutazone sodium salt
- PHENYL BUTAZONE SODIUM SALT
- sodiumphenylbutazone
- MFCD01749404
- UNII:189M850I32
保泰松钠物理化学性质
[ 密度 ]:
1.063 g/mL at 25 °C(lit.)
[ 沸点 ]:
113 °C27 mm Hg(lit.)
[ 分子式 ]:
C19H19N2NaO2
[ 分子量 ]:
330.356
[ 闪点 ]:
95 °C
[ 精确质量 ]:
330.134430
[ PSA ]:
49.99000
[ LogP ]:
4.11460
[ 折射率 ]:
n20/D 1.516(lit.)
[ 储存条件 ]:
库房通风低温干燥,与食品原料类分开存放
保泰松钠毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- UQ8300000
- CHEMICAL NAME :
- 3,5-Pyrazolidinedione, 4-butyl-1,2-diphenyl-, monosodium salt
- CAS REGISTRY NUMBER :
- 129-18-0
- LAST UPDATED :
- 199012
- DATA ITEMS CITED :
- 10
- MOLECULAR FORMULA :
- C19-H20-N2-O2.Na
- MOLECULAR WEIGHT :
- 331.40
- WISWESSER LINE NOTATION :
- T5VNNV EHJ BR& CR& E4 &-NA-
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Human - woman
- DOSE/DURATION :
- 16 mg/kg/D
- TOXIC EFFECTS :
- Lungs, Thorax, or Respiration - structural or functional change in trachea or bronchi Blood - agranulocytosis Skin and Appendages - dermatitis, other (after systemic exposure)
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 855 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 310 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity)
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 113 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 476 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 169 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 257 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 94 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 146 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
MUTATION DATA
- TYPE OF TEST :
- Mutation test systems - not otherwise specified
- TEST SYSTEM :
- Human Lymphocyte
- DOSE/DURATION :
- 2160 umol/L
- REFERENCE :
- HUMAA7 Humangenetik. (Heidelberg, Fed. Rep. Ger.) V.1-30, 1964-75. For publisher information, see HUGEDQ. Volume(issue)/page/year: 12,330,1971
保泰松钠安全信息
[ 危害码 (欧洲) ]:
C
[ 风险声明 (欧洲) ]:
R36/37/38:Irritating to eyes, respiratory system and skin .
[ 安全声明 (欧洲) ]:
S26-S36
[ 海关编码 ]:
2934100090
保泰松钠海关
[ 海关编码 ]: 2934100090
[ 中文概述 ]:
2934100090. 结构上含有一个非稠合噻唑环的化合物(不论是否氢化). 增值税率:17.0%. 退税率:9.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
[ 申报要素 ]: 品名, 成分含量, 用途
[ Summary ]:
2934100090 other compounds containing an unfused thiazole ring (whether or not hydrogenated) in the structure VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%
推荐生产厂家/供应商:
公司名:上海化源世纪贸易有限公司
区域:上海市普陀区
价格:
联系人:徐经理
公司名:上海吉至生化科技有限公司
区域:上海市奉贤区
价格:
¥176.0/10g
¥36.0/1g
¥366.0/25g
¥116.0/5g
联系人:刘佳
产品详情:保泰松钠
公司名:上海创赛科技有限公司
区域:上海市嘉定区
价格:
¥178.0/10g
¥224.0/25g
¥124.0/5g
联系人:夏言
产品详情:[Perfemiker]4-丁基-1,2-二苯基-3,5-吡唑烷二酮钠盐,97%
公司名:武汉鼎信通药业有限公司
区域:武汉市江夏区
价格:
¥需询单/1kg
$需询单/10kg
$需询单/50kg
$需询单/500kg
联系人:董浩
产品详情:保泰松钠
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相关化合物
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