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SBFI-AM

SBFI-AM用途

SBFI-AM是一种钠选择性荧光指示剂。SBFI-AM显示出Na+对K+的选择性[1]。

SBFI-AM名称

[ CAS 号 ]:
129423-53-6

[ 英文名 ]:
SBFI-AM

[英文别名 ]:

S1148_SIAL
SBFI-AM
Sodium-binding benzofuran isophthalate-AM
Sodium indicator SBFI-AM

SBFI-AM生物活性

[ 描述 ]:

SBFI-AM是一种钠选择性荧光指示剂。SBFI-AM显示出Na+对K+的选择性[1]。

[ 相关类别 ]:

研究领域 >> 其他

信号通路 >> 其他 >> 其他

[参考文献]

[1]. Minta A, et, al. Fluorescent indicators for cytosolic sodium. J Biol Chem. 1989 Nov 15;264(32):19449-57.

SBFI-AM物理化学性质

[ 密度 ]:
1.311g/cm3

[ 沸点 ]:
1110.3ºC at 760 mmHg

[ 分子式 ]:
C₅₆H₅₈N₂O₂₃

[ 分子量 ]:
1127.06000

[ 闪点 ]:
625.3ºC

[ 精确质量 ]:
1126.34000

[ PSA ]:
289.31000

[ LogP ]:
6.74620

[ 蒸汽压 ]:
0mmHg at 25°C

[ 折射率 ]:
1.567

SBFI-AMMSDS

详细MSDS(安全技术说明书)

SBFI-AM安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危险品运输编码 ]:
NONH for all modes of transport

SBFI-AM文献

Synthetic ion transporters can induce apoptosis by facilitating chloride anion transport into cells.

Nature Chemistry 6(10) , 885-92, (2014)

Anion transporters based on small molecules have received attention as therapeutic agents because of their potential to disrupt cellular ion homeostasis. However, a direct correlation between a change...

A neutrophil intrinsic impairment affecting Rab27a and degranulation in cystic fibrosis is corrected by CFTR potentiator therapy.

Blood 124(7) , 999-1009, (2014)

Studies have endeavored to reconcile whether dysfunction of neutrophils in people with cystic fibrosis (CF) is a result of the genetic defect or is secondary due to infection and inflammation. In this...

Cyclooxygenase 2 inhibitor celecoxib inhibits glutamate release by attenuating the PGE2/EP2 pathway in rat cerebral cortex endings.

J. Pharmacol. Exp. Ther. 351(1) , 134-45, (2014)

The excitotoxicity caused by excessive glutamate is a critical element in the neuropathology of acute and chronic brain disorders. Therefore, inhibition of glutamate release is a potentially valuable ...

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