2,2',4,4'-四羟基二苯甲酮

2,2',4,4'-四羟基二苯甲酮用途

【用途一】
用作医药中间体、感光材料、化妆品防紫外线添加剂等
【紫外线吸收剂】
2,2',4,4'-四羟基二苯甲酮
【131-55-5】
为苯并三唑类紫外线吸收剂中高效的紫外线吸收剂，最高紫外线吸收峰为345nm,与高聚合物的相溶性好,挥发性低,并兼具有抗氧性能,可与一般抗氧剂并用,广泛用于聚丙烯、聚乙烯, 还可用于聚氯乙烯、有机玻璃、 ABS 树脂、涂料、石油制品和橡胶等制品。另适用于聚烯烃(特别是聚氯乙烯)、聚酯、苯乙烯类、聚酰胺、聚碳酸酯等聚合物。

2,2',4,4'-四羟基二苯甲酮名称

[ CAS 号 ]:
131-55-5

[ 中文名 ]:
2,2',4,4'-四羟基二苯甲酮

[ 英文名 ]:
2,2',4,4'-Tetrahydroxybenzophenone

[中文别名 ]:

[英文别名 ]:

Seesorb 106
70A-196
2,2',4,4'-Tetrahydroxybenzophenone
BENZOPHENONE-2
2,2',4,4'-Tetrahydroxybenzophe
EINECS 205-028-9
uvinuld-50
2,2′,4,4′-tetrahydroxybenzophenone
2,2',4,4'-tetrahyroxybenzophenone
2,4,2',4'-tetrahydroxybenzophenone

2,2',4,4'-四羟基二苯甲酮物理化学性质

[ 密度 ]:
1.5±0.1 g/cm3

[ 沸点 ]:
531.2±25.0 °C at 760 mmHg

[ 熔点 ]:
198-200 °C(lit.)

[ 分子式 ]:
C₁₃H₁₀O₅

[ 分子量 ]:
246.215

[ 闪点 ]:
289.1±19.7 °C

[ 精确质量 ]:
246.052826

[ PSA ]:
97.99000

[ LogP ]:
3.16

[ 外观性状 ]:
黄色至棕色结晶粉末

[ 蒸汽压 ]:
0.0±1.5 mmHg at 25°C

[ 折射率 ]:
1.718

[ 储存条件 ]:
通风低温干燥

2,2',4,4'-四羟基二苯甲酮MSDS

详细MSDS(安全技术说明书)

2,2',4,4'-四羟基二苯甲酮毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DJ1892000

CHEMICAL NAME :: Benzophenone, 2,2',4,4'-tetrahydroxy-

CAS REGISTRY NUMBER :: 131-55-5

BEILSTEIN REFERENCE NO. :: 1914746

LAST UPDATED :: 199701

DATA ITEMS CITED :: 7

MOLECULAR FORMULA :: C13-H10-O5

MOLECULAR WEIGHT :: 246.23

WISWESSER LINE NOTATION :: QR CQ DVR BQ DQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1220 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :: Sister chromatid exchange

TEST SYSTEM :: Rodent - mouse Lymphocyte

DOSE/DURATION :: 200 ug/plate

REFERENCE :: JACTDZ Journal of the American College of Toxicology. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued. Volume(issue)/page/year: 2(5),35,1983 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X7078 No. of Facilities: 9 (estimated) No. of Industries: 1 No. of Occupations: 2 No. of Employees: 869 (estimated) No. of Female Employees: 617 (estimated)

2,2',4,4'-四羟基二苯甲酮安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H302-H315-H319-H335

[ 警示性声明 ]:
P261-P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xn:Harmful

[ 风险声明 (欧洲) ]:
R22;R36/37/38

[ 安全声明 (欧洲) ]:
S26-S36-S37/39

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ RTECS号 ]:
DJ1892000

[ 包装等级 ]:
II; III

[ 危险类别 ]:
4.1

[ 海关编码 ]:
2914501900

2,2',4,4'-四羟基二苯甲酮合成路线

详细合成路线

2,2',4,4'-四羟基二苯甲酮上下游产品

2,2',4,4'-四羟基二苯甲酮上游产品

2,2',4,4'-四羟基二苯甲酮下游产品

2,2',4,4'-四羟基二苯甲酮海关

[ 海关编码 ]: 2914501900

[ 中文概述 ]:
2914501900 其他酮酚。监管条件:无。增值税率:17.0%。退税率:9.0%。最惠国关税:5.5%。普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 丙酮报明包装

[ Summary ]:
2914501900 other ketone-phenols。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

2,2',4,4'-四羟基二苯甲酮文献

Selectivity of natural, synthetic and environmental estrogens for zebrafish estrogen receptors.

Toxicol. Appl. Pharmacol. 280(1) , 60-9, (2014)

Zebrafish, Danio rerio, is increasingly used as an animal model to study the effects of pharmaceuticals and environmental estrogens. As most of these estrogens have only been tested on human estrogen ...

Metabolism of UV-filter benzophenone-3 by rat and human liver microsomes and its effect on endocrine-disrupting activity.

Toxicol. Appl. Pharmacol. 282(2) , 119-28, (2015)

Benzophenone-3 (2-hydroxy-4-methoxybenzophenone; BP-3) is widely used as sunscreen for protection of human skin and hair from damage by ultraviolet (UV) radiation. In this study, we examined the metab...

Ultra-preconcentration and determination of selected pharmaceutical and personal care products in different water matrices by solid-phase extraction combined with dispersive liquid-liquid microextraction prior to ultra high pressure liquid chromatography tandem mass spectrometry analysis.

J. Chromatogr. A. 1355 , 26-35, (2014)

Pharmaceutical and personal care products (PPCPs) are one of the most important classes of emerging contaminants. The potential of ecological and environmental impacts associated with PPCPs are of par...

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