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葡甲胺锑酸盐

葡甲胺锑酸盐名称

[ CAS 号 ]:
133-51-7

[ 中文名 ]:
葡甲胺锑酸盐

[ 英文名 ]:
Meglumine antimonate

[中文别名 ]:

锑酸甲葡胺

[英文别名 ]:

Methylglucamine antimonate
2168-rp
Protostib {Antimonate}
glucantime
RP 2168 {Antimonate}
protostib
MFCD01725422
N-Methylglucamine antimonate
N-METHYL GLUCAMINE ANTIMONATE
N-MethylgluamineAntimoniate

葡甲胺锑酸盐物理化学性质

[ 密度 ]:
1.375g/cm3

[ 沸点 ]:
490.4ºC at 760mmHg

[ 熔点 ]:
168-170°C

[ 分子式 ]:
C₇H₁₈NO₈Sb

[ 分子量 ]:
383.995

[ 闪点 ]:
251.6ºC

[ 精确质量 ]:
383.017639

[ PSA ]:
167.55000

[ 储存条件 ]:
2-8°C

葡甲胺锑酸盐毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: LZ4370000

CHEMICAL NAME :: D-Glucitol, 1-deoxy-1-(methylamino)-, trioxoantimonate(1-)

CAS REGISTRY NUMBER :: 133-51-7

LAST UPDATED :: 199606

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C7-H17-N-O5.H-O3-Sb

MOLECULAR WEIGHT :: 366.01

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Human - child

DOSE/DURATION :: 700 mg/kg/7D

TOXIC EFFECTS :: Kidney, Ureter, Bladder - interstitial nephritis Kidney, Ureter, Bladder - urine volume increased Kidney, Ureter, Bladder - urine volume decreased

REFERENCE :: MAMEA2 Maroc Medical. (Casablanca, Morocco) V.1-55, 1921-75. Discontinued. Volume(issue)/page/year: 41,1180,1962 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intramuscular

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 27056 mg/kg/30D-I

TOXIC EFFECTS :: Blood - changes in leukocyte (WBC) count Nutritional and Gross Metabolic - weight loss or decreased weight gain Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - transaminases

REFERENCE :: HETOEA Human & Experimental Toxicology. (Macmillan Press Ltd., Brunel Road, Houndmills, Basingstoke, Hampshire, RG21 2XS, UK) V.9- 1990- Volume(issue)/page/year: 11,283,1992

葡甲胺锑酸盐安全信息

[ 危害码 (欧洲) ]:
Xi

[ 风险声明 (欧洲) ]:
R36/37/38:Irritating to eyes, respiratory system and skin .

[ 安全声明 (欧洲) ]:
S26-S36/37/39