JWH-424

JWH 018 is a synthetic cannabinoid (CB) that potently activates the central CB1 and peripheral CB2 receptors (Ki = 9.0 and 2.94 nM, respectively). This cannabimimetic compound has frequently been found in herbal blends. JWH 424 is an 8-bromonaphthyl derivative of JWH 018 which shows a reduced selectivity for CB1 over CB2 (Ki = 20.9 and 5.4 nM, respectively).

[ 密度 ]:
1.3±0.1 g/cm3

[ 沸点 ]:
572.4±25.0 °C at 760 mmHg

[ 分子式 ]:
C₂₄H₂₂BrNO

[ 分子量 ]:
420.342

[ 闪点 ]:
300.0±23.2 °C

[ 精确质量 ]:
419.088470

[ PSA ]:
22.00000

[ LogP ]:
7.63

[ 蒸汽压 ]:
0.0±1.6 mmHg at 25°C

[ 折射率 ]:
1.628

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