GLY-VAL-LEU-SER-ASN-VAL-ILE-GLY-TYR-LEU-LYS-LYS-LEU-GLY-THR-GLY-ALA-LEU-ASN-ALA-VAL-LEU-LYS-GLN: GVLSNVIGYLKKLGTGALNAVLKQ

用途

GVLSNVIGYLKKKLGTGALNAVLKQ是一种具有24个氨基酸的抗菌肽。GVLSNVIGYLKKKLGTGALNAVLKQ可能形成α-螺旋。GVLSNVIGYLKKKLGTGALNAVLKQ(PGQ)对革兰氏阴性菌、革兰氏阳性菌和酵母白色念珠菌具有活性[1]。

名称

[ CAS 号 ]:
136831-50-0

[ 中文名 ]:
GLY-VAL-LEU-SER-ASN-VAL-ILE-GLY-TYR-LEU-LYS-LYS-LEU-GLY-THR-GLY-ALA-LEU-ASN-ALA-VAL-LEU-LYS-GLN: GVLSNVIGYLKKLGTGALNAVLKQ

[ 英文名 ]:
G-V-L-S-N-V-I-G-Y-L-K-K-L-G-T-G-A-L-N-A-V-L-K-Q

[英文别名 ]:

生物活性

[ 描述 ]:

[ 相关类别 ]:

研究领域 >> 感染

研究领域 >> 炎症/免疫

信号通路 >> 抗感染 >> 细菌

[体外研究]

GVLSNVIGYLKKLGTGALNAVLKQ(PGQ)具有抗革兰氏阴性、革兰氏阳性细菌和酵母菌白色念珠菌的低抑制浓度活性[1]。

[参考文献]

[1]. K S Moore, et al. Antimicrobial peptides in the stomach of Xenopus laevis. J Biol Chem. 1991 Oct 15;266(29):19851-7.

物理化学性质

[ 分子式 ]:
C₁₁₄H₁₉₅F₃N₃₀O₃₃

[ 分子量 ]:
2570.945

[ 精确质量 ]:
2569.445557

[ PSA ]:
1037.94000

[ LogP ]:
5.60950

MSDS

详细MSDS(安全技术说明书)

安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危险品运输编码 ]:
NONH for all modes of transport

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