丙酸钠

丙酸钠用途

【用途一】
用作防腐剂，用于糕点、杨梅等防霉
【用途二】
用作杀菌剂、防霉剂
【用途三】
丙酸钠液湿酸型防腐剂，其抑菌作用受环境PH的影响。在PH5.0时最小抑菌浓度为0.01%，PH6.5时为0.5%。在酸性介质中对各类霉菌、好氧芽孢杆菌或革兰阴性杆菌由较强的抑制作用。对防止黄曲霉菌素的产生有特效，而对酵母几乎无效。此外，也作为食品的防腐剂。
【用途四】
在制革中作蒙囿剂，以提高皮革的耐碱力和鞣制的均匀性。
【用途五】
丙酸钠也是酸型食品防腐剂，其抑菌作用受环境pH值的影响。在pH值5.0时最小抑菌浓度为0.01%，pH值6.5时为0.5%。在酸性介质中对各类霉菌、革兰氏阴性杆菌或好氧芽孢杆菌有较强的抑制作用。对防止黄曲霉菌素的产生有特效，而对酵母几乎无效。在食品工业中，可用于糕点的保存，使用量2.5g/kg(以丙酸计，下同)；在3%～5%的水溶液浸泡杨梅中最大使用量50g/kg。还可作饲料的防霉剂。
【用途六】
防腐剂；防霉剂。
【用途七】
食品、饲料和防腐、防霉剂。一般添加量为0.1-0.3%。
【用途八】
杀菌剂、防霉剂。测定转氨酶。食品、饲料和防腐、防霉剂。一般添加量为0.1-0.3%。

丙酸钠名称

[ CAS 号 ]:
137-40-6

[ 中文名 ]:
丙酸钠

[ 英文名 ]:
Sodium propionate

[中文别名 ]:

丙酸鈉

[英文别名 ]:

Propionate sodium salt
deketon
propisol
whit-pro
MFCD00002759
sodium proprionate
Napropion
bioban-s
Sodium Propionate
Mycoban

丙酸钠物理化学性质

[ 沸点 ]:
141.7ºC at 760mmHg

[ 熔点 ]:
285-286 °C(lit.)

[ 分子式 ]:
C₃H₅NaO₂

[ 分子量 ]:
96.060

[ 闪点 ]:
57.7ºC

[ 精确质量 ]:
96.018723

[ PSA ]:
40.13000

[ 外观性状 ]:
白色结晶粉末

[ 蒸汽压 ]:
4.23mmHg at 25°C

[ 储存条件 ]:
库房低温,通风,干燥

[ 稳定性 ]:
Stable. Incompatible with strong oxidizing agents. Hygroscopic.

[ 水溶解性 ]:
995 g/L (20 ºC)

丙酸钠MSDS

详细MSDS(安全技术说明书)

丙酸钠毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UF7525000

CHEMICAL NAME :: Propionic acid, sodium salt

CAS REGISTRY NUMBER :: 137-40-6

LAST UPDATED :: 199701

DATA ITEMS CITED :: 10

MOLECULAR FORMULA :: C3-H5-O2.Na

MOLECULAR WEIGHT :: 96.07

WISWESSER LINE NOTATION :: QV2 &-NA-

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 8150 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - excitement Lungs, Thorax, or Respiration - dyspnea

REFERENCE :: GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 35(3),96,1970

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 6332 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NEZAAQ Nippon Eiseigaku Zasshi. Japanese Journal of Hygiene. (Nippon Eisei Gakkai, c/o Kyoto Daigaku Igakubu, Konoe-cho, Yoshida, Sakyo-ku, Kyoto 606, Japan) V.1- 1946- Volume(issue)/page/year: 28,463,1973

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 7800 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - excitement Lungs, Thorax, or Respiration - dyspnea

REFERENCE :: GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 35(3),96,1970

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 1640 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JIHTAB Journal of Industrial Hygiene and Toxicology. (Cambridge, MA) V.18-31, 1936-49. For publisher information, see AEHLAU. Volume(issue)/page/year: 31,60,1949

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 6750 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - excitement Lungs, Thorax, or Respiration - dyspnea

REFERENCE :: GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 35(3),96,1970 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 24817 mg/kg/9W-I

TOXIC EFFECTS :: Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol) Blood - other changes

REFERENCE :: GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 35(3),96,1970 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 69375 No. of Facilities: 349 (estimated) No. of Industries: 10 No. of Occupations: 12 No. of Employees: 3448 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 69375 No. of Facilities: 1499 (estimated) No. of Industries: 19 No. of Occupations: 32 No. of Employees: 29865 (estimated) No. of Female Employees: 14849 (estimated)

丙酸钠安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H312

[ 警示性声明 ]:
P280

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xn:Harmful

[ 风险声明 (欧洲) ]:
R21;R38

[ 安全声明 (欧洲) ]:
S36/37-S36/37/39-S26-S36

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
1

[ RTECS号 ]:
UF7525000

[ 海关编码 ]:
2915509000

丙酸钠合成路线

详细合成路线

丙酸钠上下游产品

丙酸钠上游产品

丙酸钠下游产品

丙酸钠制备

1.主要采用合成法。以丙酸和氢氧化钠为原料进行合成反应，然后经脱水、精制、干燥而得

2.将碳酸钠溶于热水中，在70℃慢慢加入丙酸，然后加热至沸，ph值控制在6.8～7.3，脱色，过滤，减压浓缩，冷却，过滤，干燥即为成品。反应式如下：

3.由丙酸与氢氧化钠中和，经浓缩、结晶、分离、干燥而得。

4.由丙酸与氢氧化钠或碳酸钠中和而得。

丙酸钠海关

[ 海关编码 ]: 2915509000

[ 中文概述 ]:
2915509000 丙酸盐和酯. 增值税率:17.0% 退税率:9.0% 监管条件:AB(入境货物通关单,出境货物通关单) 最惠国关税:5.5% 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ 监管条件 ]: A.入境货物通关单 B.出境货物通关单

[ 检验检疫 ]: R.进口食品卫生监督检验 S.出口食品卫生监督检验 M.进口商品检验 N.出口商品检验

[ Summary ]:
2915509000 propionic acid, its salts and esters。supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward)。VAT:17.0%。tax rebate rate:9.0%。MFN tariff:5.5%。general tariff:30.0%

丙酸钠文献

Hydrolytic pathway of 5-fluorouracil in aqueous solutions for clinical use.

J. Pharm. Biomed. Anal. 98 , 446-62, (2014)

The purpose of the study was to investigate the degradation pathway of 5-fluorouracil (FU) in the situation of commercial formulations for clinical use, namely FU dissolved in sodium hydroxide (NaOH) ...

Short-chain fatty acids and acidic pH upregulate UT-B, GPR41, and GPR4 in rumen epithelial cells of goats.

Am. J. Physiol. Regul. Integr. Comp. Physiol. 308(4) , R283-93, (2015)

Currently, the mechanism(s) responsible for the regulation of urea transporter B (UT-B) expression levels in the epithelium of the rumen remain unclear. We hypothesized that rumen fermentation product...

Free fatty acid receptor 2, a candidate target for type 1 diabetes, induces cell apoptosis through ERK signaling.

J. Mol. Endocrinol. 53(3) , 367-80, (2014)

Recent reports have highlighted the roles of free fatty acid receptor 2 (FFAR2) in the regulation of metabolic and inflammatory processes. However, the potential function of FFAR2 in type 1 diabetes (...

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丙酸钠