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车叶草苷

车叶草苷用途

Asperuloside 是一种环烯醚萜,来源于蛇舌草,具有抗炎活性。Asperuloside 可抑制诱导型一氧化氮合酶 (iNOS),抑制 NF-κB 和 MAPK 信号通路。

车叶草苷名称

[ CAS 号 ]:
14259-45-1

[ 中文名 ]:
车叶草苷

[ 英文名 ]:
Asperuloside

[英文别名 ]:

Asperulosid
RUBICHLORIC ACID
ASPERULOSIDE

车叶草苷生物活性

[ 描述 ]:

Asperuloside 是一种环烯醚萜,来源于蛇舌草,具有抗炎活性。Asperuloside 可抑制诱导型一氧化氮合酶 (iNOS),抑制 NF-κB 和 MAPK 信号通路。

[ 相关类别 ]:

信号通路 >> 免疫及炎症 >> 一氧化氮合酶

研究领域 >> 炎症/免疫

[参考文献]

[1]. He J, et al. Asperuloside and Asperulosidic Acid Exert an Anti-Inflammatory Effect via Suppression of the NF-κB and MAPK Signaling Pathways in LPS-Induced RAW 264.7 Macrophages. Int J Mol Sci. 2018 Jul 12;19(7).

车叶草苷物理化学性质

[ 密度 ]:
1.6±0.1 g/cm3

[ 沸点 ]:
704.2±60.0 °C at 760 mmHg

[ 熔点 ]:
131-132°

[ 分子式 ]:
C₁₈H₂₂O₁₁

[ 分子量 ]:
414.361

[ 闪点 ]:
254.1±26.4 °C

[ 精确质量 ]:
414.116211

[ PSA ]:
161.21000

[ LogP ]:
-3.28

[ 蒸汽压 ]:
0.0±5.1 mmHg at 25°C

[ 折射率 ]:
1.635

[ 储存条件 ]:
2-8C

车叶草苷MSDS

详细MSDS(安全技术说明书)

车叶草苷安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H302

[ 危害码 (欧洲) ]:
Xn

[ 风险声明 (欧洲) ]:
22

[ 危险品运输编码 ]:
NONH for all modes of transport

车叶草苷文献

Chemical constituents of the fruits of Morinda citrifolia (Noni) and their antioxidant activity.

J. Nat. Prod. 68 , 592-5, (2005)

Purification of a n-BuOH-soluble partition of the MeOH extract of Morinda citrifolia (Noni) fruits led to the isolation of two new iridoid glucosides, 6alpha-hydroxyadoxoside (1) and 6beta,7beta-epoxy...

[Chemical constituents from root of Lasianthus acuminatissimus I].

Zhongguo Zhong Yao Za Zhi 31(2) , 133-5, (2006)

To investigate the chemical constituents from the root of Lasianthus acuminatissimus of Rubiaceae.Normal, reverse phase silica gel, macroporous resin column and HPLC chromatography were used for isola...

[Isolation and identification of chemical constituents from Hedyotis chrysotricha (Palib.) Merr].

Zhongguo Zhong Yao Za Zhi 17(2) , 98-100, 127, (1992)

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