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二硝托胺

二硝托胺用途

Dinitolmid是家禽饲料添加剂,用来防止球虫病感染。

二硝托胺名称

[ CAS 号 ]:
148-01-6

[ 中文名 ]:
二硝托胺

[ 英文名 ]:
Dinitolmide

[中文别名 ]:

[英文别名 ]:

MFCD00007985
Benzamide, 2-methyl-3,5-dinitro-
2-Methyl-3,5-dinitrobenzamide
EINECS 204-499-8
Dinitolmide
3,5-Dinitro-2-methylbenzamide

二硝托胺生物活性

[ 描述 ]:

Dinitolmid是家禽饲料添加剂,用来防止球虫病感染。

[ 相关类别 ]:

信号通路 >> 抗感染 >> 寄生物

研究领域 >> 感染

[相关活性小分子]

二硝托胺物理化学性质

[ 密度 ]:
1.5±0.1 g/cm3

[ 沸点 ]:
298.0±40.0 °C at 760 mmHg

[ 熔点 ]:
183-185 °C(lit.)

[ 分子式 ]:
C₈H₇N₃O₅

[ 分子量 ]:
225.158

[ 闪点 ]:
134.0±27.3 °C

[ 精确质量 ]:
225.038574

[ PSA ]:
134.73000

[ LogP ]:
1.01

[ 外观性状 ]:
淡黄色,结晶固体

[ 蒸汽压 ]:
0.0±0.6 mmHg at 25°C

[ 折射率 ]:
1.636

[ 储存条件 ]:
0-6°C

二硝托胺MSDS

详细MSDS(安全技术说明书)

二硝托胺毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: XS4200000

CHEMICAL NAME :: o-Toluamide, 3,5-dinitro-

CAS REGISTRY NUMBER :: 148-01-6

BEILSTEIN REFERENCE NO. :: 1990738

LAST UPDATED :: 199712

DATA ITEMS CITED :: 14

MOLECULAR FORMULA :: C8-H7-N3-O5

MOLECULAR WEIGHT :: 225.18

WISWESSER LINE NOTATION :: ZVR B1 CNW ENW

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 600 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 75 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :: DNA repair

TEST SYSTEM :: Bacteria - Bacillus subtilis

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 77,21,1980 *** REVIEWS *** ACGIH TLV-Not classifiable as a human carcinogen DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 ACGIH TLV-TWA 5 mg/m3 DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-AUSTRALIA:TWA 5 mg/m3 JAN 1993 OEL-BELGIUM:TWA 5 mg/m3 JAN 1993 OEL-FRANCE:TWA 5 mg/m3 JAN 1993 OEL-THE NETHERLANDS:TWA 5 mg/m3 JAN 1993 OEL-SWITZERLAND:TWA 5 mg/m3 JAN 1993 OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH RECOMMENDED EXPOSURE LEVEL (REL) : NIOSH REL TO DINITROLMIDE-air:10H TWA 5 mg/m3 REFERENCE : NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda. Volume(issue)/page/year: DHHS #92-100,1992

二硝托胺安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H302

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xn: Harmful;F: Flammable;

[ 风险声明 (欧洲) ]:
R22;R36;R20/21/22;R11

[ 安全声明 (欧洲) ]:
S26-S36-S16

[ 危险品运输编码 ]:
UN 1648 3/PG 2

[ WGK德国 ]:
3

[ RTECS号 ]:
XS4200000

[ 海关编码 ]:
2309901000

二硝托胺上下游产品

二硝托胺上游产品

二硝托胺下游产品

二硝托胺制备

1.合成路线与维生素B1生产类似，可参见维生素B1（03002）。

2.以邻甲基酸为原料，经硝化得3，5-二硝基邻甲基苯甲酸，再用二氯亚砜酰氯化、氨水氨化得产品。

二硝托胺海关

[ 海关编码 ]: 2924299090

[ 中文概述 ]:
2924299090. 其他环酰胺（包括环氨基甲酸酯）（包括其衍生物以及他们的盐）. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 包装

[ Summary ]:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

二硝托胺文献

Sensitivity of field isolates of Eimeria tenella to anticoccidial drugs in the chicken.

Res. Vet. Sci. 47(1) , 125-8, (1989)

Thirty isolates of Eimeria tenella obtained from broiler and breeder farms were examined for their sensitivity to anticoccidial drugs. All were sensitive to robenidine, 28 were sensitive to methyl ben...

Effects of different coccidiostats on performance of large white turkeys.

Poult. Sci. 70(2) , 241-9, (1991)

Two trials were conducted to evaluate the effects of feeding various anticoccidial products to turkeys to 8 wk and then growing to market age (16 wk for hens and 20 wk for toms). Anticoccidials evalua...

Efficacy of different anticoccidials against experimental coccidiosis in large white turkeys.

Poult. Sci. 70(2) , 289-92, (1991)

Two trials were conducted to compare the efficacy of currently approved anticoccidials for turkeys against challenge using a field isolate of mixed Eimeria species; E. adenoides, E. gallopavonis, and ...

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