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4-硝基苯基-N-乙酰-beta-D-半乳胺

4-硝基苯基-N-乙酰-beta-D-半乳胺用途

4-硝基苯基-N-乙酰基-β-D-半乳糖胺对GlcNAc和GalNAc具有抑制活性,Kis分别为1.15mm和0.51mm。4-硝基苯基-N-乙酰基-β-D-半乳糖胺是从滴虫胎儿中提取的[1]

4-硝基苯基-N-乙酰-beta-D-半乳胺名称

[ CAS 号 ]:
14948-96-0

[ 中文名 ]:
4-硝基苯基-N-乙酰-β-D-氨基半乳糖苷

[ 英文名 ]:
4-Nitrophenyl N-acetyl-β-D-galactosaminide

[中文别名 ]:

4-硝基苯基-N-乙酰-beta-D-半乳胺

[英文别名 ]:

EINECS 239-024-3
MFCD00150920
4-nitrophenyl N-acetyl-beta-D-galactosaminide
4-Nitrophenyl-N-acetyl-β-D-galactosaminide
4-Nitrophenyl N-acetyl-β-D-galactosaminide

4-硝基苯基-N-乙酰-beta-D-半乳胺生物活性

[ 描述 ]:

4-硝基苯基-N-乙酰基-β-D-半乳糖胺对GlcNAc和GalNAc具有抑制活性,Kis分别为1.15mm和0.51mm。4-硝基苯基-N-乙酰基-β-D-半乳糖胺是从滴虫胎儿中提取的[1]

[ 相关类别 ]:

研究领域 >> 癌症

[ 靶点 ]

Ki: 1.15 mM (GlcNAc), 0.51 mM (GalNAc)[1]

[参考文献]

[1]. Edwards RG, et al. The purification and properties of a beta-N-acetylhexosaminidase from Trichomonas foetus. Biochem J. 1975 Oct;151(1):145-8. doi: 10.1042/bj1510145

4-硝基苯基-N-乙酰-beta-D-半乳胺物理化学性质

[ 密度 ]:
1.5±0.1 g/cm3

[ 沸点 ]:
694.7±55.0 °C at 760 mmHg

[ 熔点 ]:
181ºC

[ 分子式 ]:
C₁₄H₁₈N₂O₈

[ 分子量 ]:
342.301

[ 闪点 ]:
374.0±31.5 °C

[ 精确质量 ]:
342.106323

[ PSA ]:
154.07000

[ LogP ]:
0.00

[ 外观性状 ]:
灰白色粉末

[ 蒸汽压 ]:
0.0±2.3 mmHg at 25°C

[ 折射率 ]:
1.620

[ 储存条件 ]:
−20°C

[ 水溶解性 ]:
DMF: 50 mg/mL, clear, yellow-green

4-硝基苯基-N-乙酰-beta-D-半乳胺MSDS

4-硝基苯基-N-乙酰-beta-D-半乳胺安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危害码 (欧洲) ]:
Xi

[ 安全声明 (欧洲) ]:
22-24/25

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

4-硝基苯基-N-乙酰-beta-D-半乳胺合成路线

4-硝基苯基-N-乙酰-beta-D-半乳胺上下游产品

4-硝基苯基-N-乙酰-beta-D-半乳胺上游产品

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4-硝基苯基-N-乙酰-beta-D-半乳胺文献

Binding of simple carbohydrates and some of their chromophoric derivatives to soybean agglutinin as followed by titrimetric procedures and stopped flow kinetics.

J. Biol. Chem. 259(11) , 7067-74, (1984)

The number of carbohydrate-binding sites of the GalNAc-specific lectin is four per tetramer. The binding parameters of N-acetyl-D-galactosamine and methyl-N-acetyl-alpha-D- galactosaminide , were dete...

Syntheses of the 3- and 4-thio analogues of 4-nitrophenyl 2-acetamido-2-deoxy-beta-D-gluco- and galactopyranoside.

Carbohydr. Res. 342(15) , 2212-22, (2007)

The syntheses of 4-nitrophenyl beta-glycosides of the 3-thio and 4-thio analogues of the two principal 2-acetamido-2-deoxy-hexoses found in living systems, GlcNAc and GalNAc, are described. While synt...

Chitin oligosaccharide synthesis by rhizobia and zebrafish embryos starts by glycosyl transfer to O4 of the reducing-terminal residue.

Biochemistry 38(13) , 4045-52, (1999)

Lipochitin oligosaccharides are organogenesis-inducing signal molecules produced by rhizobia to establish the formation of nitrogen-fixing root nodules in leguminous plants. Chitin oligosaccharide bio...

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