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Adenosine 2',5'-diphosphate sodium

用途

Adenosine 2',5'-diphosphate sodium 是一种竞争性 P2Y1 拮抗剂。Adenosine 2',5'-diphosphate sodium 对重组人和人血小板 P2X1 受体具有非选择性拮抗作用。

名称

[ CAS 号 ]:
154146-84-6

[ 中文名 ]:
腺苷2',5'-二磷酸钠盐

[ 英文名 ]:
Adenosine 2',5'-diphosphate sodium

生物活性

[ 描述 ]:

Adenosine 2',5'-diphosphate sodium 是一种竞争性 P2Y1 拮抗剂。Adenosine 2',5'-diphosphate sodium 对重组人和人血小板 P2X1 受体具有非选择性拮抗作用。

[ 相关类别 ]:

研究领域 >> 其他
信号通路 >> G 蛋白偶联受体/G 蛋白 >> P2Y受体

[ 靶点 ]

Human Endogenous Metabolite


[体外研究]

腺苷2',5'-二磷酸非选择性拮抗血小板P2X1离子通道[1]。

[参考文献]

[1]. Boyer JL, et al. Identification of competitive antagonists of the P2Y1 receptor. Mol Pharmacol. 1996;50(5):1323-1329.

[2]. Toth-Zsamboki E, et al. The P2Y1 receptor antagonist adenosine-2',5'-diphosphate non-selectively antagonizes the platelet P2X1 ion channel. Thromb Haemost. 2001;86(5):1338-1339.

物理化学性质

[ 分子式 ]:
C10H15N5O10P2.xNa

[ 储存条件 ]:
-20 °C,密封,干燥

安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危险品运输编码 ]:
NONH for all modes of transport

文献

Identification of competitive antagonists of the P2Y1 receptor.

Mol. Pharmacol. 50 , 1323-1329, (1996)

Although P2 receptors mediate a myriad of physiological effects of extracellular adenine nucleotides, study of this broad class of receptors has been compromised by a lack of P2 receptor-selective ant...

P2y1 and P2y2 receptor-operated Ca2+ signals in primary cultures of cardiac microvascular endothelial cells.

Microvasc. Res. 61 , 240-252, (2001)

Intracellular Ca2+ signals elicited by nucleotide agonists were investigated in primary cultures of rat cardiac microvascular endothelial cells using the fura-2 technique. UTP increased the intracellu...

Characterisation of pea cytosolic glutathione reductase expressed in transgenic tobacco.

Planta 211 , 537-545, (2000)

Expression in transgenic tobacco (Nicotiana tabacum L.) of a pea (Pisum sativum L.) GOR2 cDNA, encoding an isoform of glutathione reductase (GOR2), resulted in a 3- to 7-fold elevation of total foliar...


更多文献

推荐生产厂家/供应商:

公司名:上海化源世纪贸易有限公司

区域:上海市普陀区

价格:

联系人:徐经理

产品详情:Adenosine 2',5'-diphosphate sodium salt?


公司名:上海阿拉丁生化科技股份有限公司

区域:上海市浦东新区

价格:
¥549.0/5mg ¥需询单/1g ¥需询单/1g ¥需询单/1g

联系人:阿拉丁

产品详情:腺苷2',5'-二磷酸钠盐


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相关化合物

CAS号[154146-84-6]化源网提供[Adenosine 2',5'-diphosphate sodium]MSDS、说明、性质、英文名、生产厂家、作用/用途、分子量、密度、沸点、熔点、结构式等。>>电脑版:Adenosine 2',5'-diphosphate sodium

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