<生产厂家 价格>

ASN-ASP-ASP-CYS-GLU-LEU-CYS-VAL-ASN-VAL-ALA-CYS-THR-GLY-CYS-LEU(DISULFIDE BRIDGE: CYS4-CYS12,CYS7-CYS15)

用途

Uroguanylin (human) 是在转移性结直肠癌肿瘤中表达的观音酰环化酶(GCC)受体的天然配体。Guanylyl Cyclase 在人结肠癌动物模型具有抗肿瘤作用。

名称

[ CAS 号 ]:
154525-25-4

[ 中文名 ]:
ASN-ASP-ASP-CYS-GLU-LEU-CYS-VAL-ASN-VAL-ALA-CYS-THR-GLY-CYS-LEU(DISULFIDE BRIDGE: CYS4-CYS12,CYS7-CYS15)

[ 英文名 ]:
Uroguanylin Topoisomer A (human) trifluoroacetate salt

[英文别名 ]:

生物活性

[ 描述 ]:

Uroguanylin (human) 是在转移性结直肠癌肿瘤中表达的观音酰环化酶(GCC)受体的天然配体。Guanylyl Cyclase 在人结肠癌动物模型具有抗肿瘤作用。

[ 相关类别 ]:

研究领域 >> 癌症
信号通路 >> G 蛋白偶联受体/G 蛋白 >> 鸟苷酸环化酶

[参考文献]

[1]. Lewis DK, et al. Hypertrehalosemic hormone in a cockroach: molecular cloning and expression. Mol Cell Endocrinol. 1997;130(1-2):101-108.  

物理化学性质

[ 分子式 ]:
C64H102N18O26S4

[ 分子量 ]:
1667.86000

[ 精确质量 ]:
1666.61000

[ PSA ]:
819.33000

安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

文献

Characterization of immunological cross-reactivity between enterotoxigenic Escherichia coli heat-stable toxin and human guanylin and uroguanylin.

Infect. Immun. 82(7) , 2913-22, (2014)

Enterotoxigenic Escherichia coli (ETEC) expressing the heat-stable toxin (ST) (human-type [STh] and porcine-type [STp] variants) is among the five most important enteric pathogens in young children li...

A uroguanylin-GUCY2C endocrine axis regulates feeding in mice.

J. Clin. Invest. 121 , 3578-3588, (2011)

Intestinal enteroendocrine cells are critical to central regulation of caloric consumption, since they activate hypothalamic circuits that decrease appetite and thereby restrict meal size by secreting...

Uroguanylin: structure and activity of a second endogenous peptide that stimulates intestinal guanylate cyclase.

Proc. Natl. Acad. Sci. U. S. A. 90 , 10464, (1993)

The intestinal hormone guanylin and bacterial heat-stable enterotoxins (STs) are members of a peptide family that activates intestinal membrane guanylate cyclase. Two different peptides that activate ...


更多文献

推荐生产厂家/供应商：

公司名：南京肽业生物科技有限公司

区域：南京市六合区

价格：
￥需询单/10g ￥需询单/100g ￥需询单/1kg ￥需询单/10kg

联系人：范经理

产品详情：asn-asp-asp-cys-glu-leu-cys-val-asn-val-ala-cys-thr-gly-cys-leu

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ASN-ASP-ASP-CYS-GLU-LEU-CYS-VAL-ASN-VAL-ALA-CYS-THR-GLY-CYS-LEU(DISULFIDE BRIDGE: CYS4-CYS12,CYS7-CYS15)供应商

热门化合物

CAS号[154525-25-4]化源网提供[ASN-ASP-ASP-CYS-GLU-LEU-CYS-VAL-ASN-VAL-ALA-CYS-THR-GLY-CYS-LEU(DISULFIDE BRIDGE: CYS4-CYS12,CYS7-CYS15)]MSDS、说明、性质、英文名、生产厂家、作用/用途、分子量、密度、沸点、熔点、结构式等。>>电脑版：ASN-ASP-ASP-CYS-GLU-LEU-CYS-VAL-ASN-VAL-ALA-CYS-THR-GLY-CYS-LEU(DISULFIDE BRIDGE: CYS4-CYS12,CYS7-CYS15)

标题：154525-25-4_CAS号:154525-25-4_ASN-ASP-ASP-CYS-GLU-LEU-CYS-VAL-ASN-VAL-ALA-CYS-THR-GLY-CYS-LEU(DISULFIDE BRIDGE: CYS4-CYS12,CYS7-CYS15) - 化源网 地址：https://www.chemsrc.com/amp/cas/154525-25-4_444840.html