帕拉米松乙酸酯
帕拉米松乙酸酯用途
帕拉米松乙酸酯名称
[ CAS 号 ]:
1597-82-6
[ 中文名 ]:
帕拉米松乙酸酯
[ 英文名 ]:
Paramethasone Acetate
[中文别名 ]:
[英文别名 ]:
- PARAMETHASONE ACETATE
- DSSTox_CID_3422
- Paramethasone-21-acetate
帕拉米松乙酸酯生物活性
帕拉米松乙酸酯物理化学性质
[ 密度 ]:
1.29 g/cm1.29 g/cm3
[ 沸点 ]:
584.2ºC at 760 mmHg
[ 熔点 ]:
>148°C (dec.) (lit.)
[ 分子式 ]:
C24H31FO6
[ 分子量 ]:
434.49800
[ 闪点 ]:
307.1ºC
[ 精确质量 ]:
434.21000
[ PSA ]:
100.90000
[ LogP ]:
2.32240
[ 外观性状 ]:
白色至米白色固体
[ 蒸汽压 ]:
4.42E-16mmHg at 25°C
[ 折射率 ]:
1.569
[ 储存条件 ]:
2-8°C
帕拉米松乙酸酯毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- TU4025000
- CHEMICAL NAME :
- Pregna-1,4-diene-3,20-dione, 6-alpha-fluoro-11-beta,17,21-trihydroxy-16-alpha-meth yl-, 21-acetate
- CAS REGISTRY NUMBER :
- 1597-82-6
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 6
- MOLECULAR FORMULA :
- C24-H31-F-O6
- MOLECULAR WEIGHT :
- 434.55
- WISWESSER LINE NOTATION :
- L E5 B666 OV AHTTT&J A1 CQ E1 FV1OV1 FQ G1 LF
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 392 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 18,185,1971
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >1 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,588,1982 ** REPRODUCTIVE DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Unreported
- DOSE :
- 10500 ug/kg
- SEX/DURATION :
- female 1-21 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)
- REFERENCE :
- NFGZAD Nippon Funin Gakkai Zasshi. Japanese Journal of Fertility and Sterility. (Nippon Funin Gakkai, 1-1 Sadohara-cho, Ichigaya, Shinjuku-ku, Toyko 162, Japan) V.1- 1956- Volume(issue)/page/year: 13,211,1968
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Unreported
- DOSE :
- 2625 ug/kg
- SEX/DURATION :
- female 1-21 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Effects on Embryo or Fetus - extra-embryonic structures (e.g., placenta, umbilical cord)
- REFERENCE :
- NFGZAD Nippon Funin Gakkai Zasshi. Japanese Journal of Fertility and Sterility. (Nippon Funin Gakkai, 1-1 Sadohara-cho, Ichigaya, Shinjuku-ku, Toyko 162, Japan) V.1- 1956- Volume(issue)/page/year: 13,211,1968 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - A1177 No. of Facilities: 33 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 297 (estimated)
帕拉米松乙酸酯安全信息
[ 危害码 (欧洲) ]:
Xn
推荐生产厂家/供应商:
公司名:上海化源世纪贸易有限公司
区域:上海市普陀区
价格:
联系人:徐经理
产品详情:帕拉米松乙酸酯
公司名:上海源溪生物科技有限公司
区域:上海市浦东新区
价格:
¥需询单/1g
联系人:赖经理
公司名:武汉壹加壹生物科技有限公司
区域:武汉市江夏区
价格:
¥需询单/1kg
联系人:刘经理
产品详情:帕拉米松乙酸酯
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相关化合物
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