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4-氯甲基联苯

4-氯甲基联苯名称

[ CAS 号 ]:
1667-11-4

[ 中文名 ]:
4-氯甲基联苯

[ 英文名 ]:
4-(Chloromethyl)biphenyl

[中文别名 ]:

4-(氯甲基)联苯

[英文别名 ]:

4-(Chloromethyl)-1,1'-biphenyl
4-(Chloromethyl)biphenyl
1-(chloromethyl)-4-phenylbenzene
1,1'-Biphenyl, 4-(chloromethyl)-
EINECS 216-786-5
Biphenyl, 4- (chloromethyl)-
MFCD00000917

4-氯甲基联苯物理化学性质

[ 密度 ]:
1.1±0.1 g/cm3

[ 沸点 ]:
322.4±21.0 °C at 760 mmHg

[ 熔点 ]:
70-73 °C(lit.)

[ 分子式 ]:
C₁₃H₁₁Cl

[ 分子量 ]:
202.679

[ 闪点 ]:
143.2±14.7 °C

[ 精确质量 ]:
202.054932

[ LogP ]:
4.24

[ 外观性状 ]:
白色-灰白色结晶粉末

[ 蒸汽压 ]:
0.0±0.7 mmHg at 25°C

[ 折射率 ]:
1.579

[ 储存条件 ]:
库房低温,通风,干燥

4-氯甲基联苯MSDS

4-氯甲基联苯毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DV2087000

CHEMICAL NAME :: Biphenyl, 4-(chloromethyl)-

CAS REGISTRY NUMBER :: 1667-11-4

BEILSTEIN REFERENCE NO. :: 1863327

LAST UPDATED :: 199710

DATA ITEMS CITED :: 11

MOLECULAR FORMULA :: C13-H11-Cl

MOLECULAR WEIGHT :: 202.69

WISWESSER LINE NOTATION :: G1R DR

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intraperitoneal

DOSE :: 250 mg/kg

SEX/DURATION :: male 5 day(s) pre-mating

TOXIC EFFECTS :: Reproductive - Paternal Effects - spermatogenesis (incl. genetic material, sperm morphology, motility, and count)

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

DOSE :: 2500 mg/kg

SEX/DURATION :: male 5 day(s) pre-mating

TOXIC EFFECTS :: Reproductive - Paternal Effects - spermatogenesis (incl. genetic material, sperm morphology, motility, and count)

MUTATION DATA

TYPE OF TEST :: Morphological transformation

TEST SYSTEM :: Rodent - hamster Kidney

DOSE/DURATION :: 2500 ug/L

REFERENCE :: CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1980- Volume(issue)/page/year: 2,33,1981

4-氯甲基联苯安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H315-H319-H335

[ 警示性声明 ]:
P261-P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xi:Irritant;

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
S26-S36

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ RTECS号 ]:
DV2087000

[ 海关编码 ]:
2903999090

4-氯甲基联苯合成路线

4-氯甲基联苯上下游产品

4-氯甲基联苯上游产品

4-氯甲基联苯下游产品

4-氯甲基联苯海关

[ 海关编码 ]: 2903999090

[ 中文概述 ]:
2903999090 其他芳烃卤化衍生物. 增值税率:17.0% 退税率:9.0% 监管条件:无最惠国关税:5.5% 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2903999090 halogenated derivatives of aromatic hydrocarbons VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

4-氯甲基联苯文献

The biological activity of 4-chloromethylbiphenyl, benzyl chloride and 4-hydroxymethylbiphenyl in 4 short-term tests for carcinogenicity. A report of an individual study in the UKEMS genotoxicity trial 1981.

Mutat. Res. 119(2) , 121-33, (1983)

4-Chloromethylbiphenyl (4CMB), benzyl chloride (BC) and 4-hydroxymethyl-biphenyl (4HMB) were tested for biological activity in the following assays: (i) the Salmonella/microsome assay; (ii) a bacteria...

The use of cultured mammalian cells the UKEMS collaborative genotoxicity trial (1981).

Mutat. Res. 100(1-4) , 271-6, (1982)

The effects of 4CMB, 4HMB and BC in the micronucleus test.

Mutat. Res. 100(1-4) , 353-6, (1982)

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