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ALPHA-甲基-GAMMA-丁内酯

ALPHA-甲基-GAMMA-丁内酯用途

有机合成中间体

ALPHA-甲基-GAMMA-丁内酯名称

[ CAS 号 ]:
1679-47-6

[ 中文名 ]:
α-甲基-γ-丁内酯

[ 英文名 ]:
Alpha-Methyl-Gamma-Butyrolactone

[中文别名 ]:

[英文别名 ]:

MFCD00005396
α-Methyl-γ-butyrolactone
3-Methyldihydrofuran-2(3H)-one
EINECS 216-846-0
Dihydro-3-methyl-2(3H)-furanone

ALPHA-甲基-GAMMA-丁内酯物理化学性质

[ 密度 ]:
1.04g/cm3

[ 沸点 ]:
78ºC(10 torr)

[ 分子式 ]:
C₅H₈O₂

[ 分子量 ]:
100.11600

[ 闪点 ]:
75ºC

[ 精确质量 ]:
100.05200

[ PSA ]:
26.30000

[ LogP ]:
0.56940

[ 外观性状 ]:
液体;Colorless to Almost colorless clear liquid

[ 蒸汽压 ]:
0.386mmHg at 25°C

[ 折射率 ]:
n20/D 1.432(lit.)

[ 储存条件 ]:
室温，干燥，密封

[ 水溶解性 ]:
THF: soluble

ALPHA-甲基-GAMMA-丁内酯MSDS

ALPHA-甲基-GAMMA-丁内酯安全信息

[ 个人防护装备 ]:
Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ 危害码 (欧洲) ]:
F+

[ 安全声明 (欧洲) ]:
S23

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ 海关编码 ]:
2932209090

ALPHA-甲基-GAMMA-丁内酯合成路线

ALPHA-甲基-GAMMA-丁内酯上下游产品

ALPHA-甲基-GAMMA-丁内酯上游产品

ALPHA-甲基-GAMMA-丁内酯下游产品

ALPHA-甲基-GAMMA-丁内酯制备

1. 烟草：FC，9， 18。

ALPHA-甲基-GAMMA-丁内酯海关

[ 海关编码 ]: 2932209090

[ 中文概述 ]:
2932209090. 其他内酯. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2932209090. other lactones. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

ALPHA-甲基-GAMMA-丁内酯文献

Characterization of the PON1 active site using modeling simulation, in relation to PON1 lactonase activity

Bioorg. Med. Chem. 16 , 7504-9, (2008)

Paraoxonase1 (PON1) is a HDL bound enzyme and many of the anti-atherogenic properties of HDL are attributed to PON1. The enzyme precise mechanism of protective action and its endogenous substrate rema...

Enantioselectivity of alpha-benzyl-alpha-methyl-gamma-butyrolactone-mediated modulation of anticonvulsant activity and GABA(A) receptor function.

J. Pharmacol. Exp. Ther. 309(2) , 677-83, (2004)

Alkyl-substituted butyrolactones have both inhibitory and stimulatory effects on GABA(A) receptors. Lactones with small alkyl substitutions at the alpha-position positively modulate the channel, where...

Sites of reaction of pilocarpine.

J. Am. Soc. Mass Spectrom. 10(3) , 209-16, (1999)

Analysis of the sites of reaction of a biologically important compound, pilocarpine, a molecule with imidazole and butyrolactone rings connected by a methylene bridge, has been accomplished in a quadr...

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