<生产厂家价格>

苯并[e]芘

苯并[e]芘用途

Benzo[e]pyrene存在于化石燃料中,是多芳烃化合物家族的剧毒成员。

苯并[e]芘名称

[ CAS 号 ]:
192-97-2

[ 中文名 ]:
苯并[e]芘

[ 英文名 ]:
Benzo[e]pyrene

[中文别名 ]:

[英文别名 ]:

4,5-Benzopyrene
1,2-Benzpyrene,4,5-Benzpyrene
EINECS 205-892-7
Benzo[l]pyrene
MFCD00003605
9,10-Benzpyrene
Benzo(a)pyrene
benzo<e>pyrene
Benzo(l)pyrene
Benzo(e)pyrene

苯并[e]芘生物活性

[ 描述 ]:

Benzo[e]pyrene存在于化石燃料中,是多芳烃化合物家族的剧毒成员。

[ 相关类别 ]:

研究领域 >> 其他

信号通路 >> 其他 >> 其他

[参考文献]

[1]. Schwarz FP, et al Fluorescence measurements of benzene, naphthalene, anthracene, pyrene, fluoranthene, and benzo(e)pyrene in water. Anal Chem. 1976 Mar;48(3):524-8

苯并[e]芘物理化学性质

[ 密度 ]:
1.3±0.1 g/cm3

[ 沸点 ]:
467.5±12.0 °C at 760 mmHg

[ 熔点 ]:
177-180ºC(lit.)

[ 分子式 ]:
C₂₀H₁₂

[ 分子量 ]:
252.309

[ 闪点 ]:
228.6±13.7 °C

[ 精确质量 ]:
252.093903

[ LogP ]:
6.40

[ 蒸汽压 ]:
0.0±0.6 mmHg at 25°C

[ 折射率 ]:
1.887

[ 储存条件 ]:
通风低温干燥

苯并[e]芘MSDS

苯并[e]芘毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DJ4200000

CHEMICAL NAME :: Benzo(e)pyrene

CAS REGISTRY NUMBER :: 192-97-2

BEILSTEIN REFERENCE NO. :: 1911334

LAST UPDATED :: 199710

DATA ITEMS CITED :: 40

MOLECULAR FORMULA :: C20-H12

MOLECULAR WEIGHT :: 252.32

WISWESSER LINE NOTATION :: L D6666 B6 2AB TJ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 360 mg/kg/43W-I

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Gastrointestinal - tumors

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 240 mg/kg/30W-I

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Skin and Appendages - tumors

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 160 mg/kg

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Tumorigenic - facilitates action of known carcinogen

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 140 mg/kg/37W-I

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Tumorigenic - facilitates action of known carcinogen

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 516 mg/kg/43W-I

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Skin and Appendages - tumors

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intraperitoneal

DOSE :: 300 mg/kg

SEX/DURATION :: female 8 day(s) after conception

TOXIC EFFECTS :: Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Specific Developmental Abnormalities - musculoskeletal system

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intraperitoneal

DOSE :: 150 mg/kg

SEX/DURATION :: female 8 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)

TYPE OF TEST :: Micronucleus test

TYPE OF TEST :: DNA adduct

TYPE OF TEST :: Sister chromatid exchange

MUTATION DATA

TYPE OF TEST :: Sister chromatid exchange

TEST SYSTEM :: Rodent - hamster Ovary

DOSE/DURATION :: 1 umol/L

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 53,284,1978 *** REVIEWS *** IARC Cancer Review:Animal Limited Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 3,137,1973 IARC Cancer Review:Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 32,225,1983 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 32,225,1983 IARC Cancer Review:Group 3 IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,56,1987

苯并[e]芘安全信息

[ 符号 ]:

GHS08, GHS09

[ 信号词 ]:
Danger

[ 危害声明 ]:
H350-H410

[ 警示性声明 ]:
P201-P273-P308 + P313-P501

[ 个人防护装备 ]:
Eyeshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ 危害码 (欧洲) ]:
T,N,Xn,F

[ 风险声明 (欧洲) ]:
45-50/53-67-65-38-11

[ 安全声明 (欧洲) ]:
S45;S53;S60;S61;S36/S37/S39

[ 危险品运输编码 ]:
UN 3077 9/PG 3

[ WGK德国 ]:
3

[ RTECS号 ]:
DJ4200000

[ 包装等级 ]:
III

[ 危险类别 ]:
6.1(b)

苯并[e]芘合成路线

苯并[e]芘上下游产品

苯并[e]芘上游产品

苯并[e]芘下游产品

苯并[e]芘文献

Detection of benz[j]aceanthrylene in urban air and evaluation of its genotoxic potential.

Environ. Sci. Technol. 49(5) , 3101-9, (2015)

Benz[j]aceanthrylene (B[j]A) is a cyclopenta-fused polycyclic aromatic hydrocarbon with strong mutagenic and carcinogenic effects. We have identified B[j]A in air particulate matter (PM) in samples co...

Potential of goat probiotic to bind mutagens.

Anaerobe 28 , 8-12, (2014)

The mutagen binding ability of the goat probiotics (Lactobacillus reuteri DDL 19, Lactobacillus alimentarius DDL 48, Enterococcus faecium DDE 39, and Bifidobacterium bifidum DDBA) was evaluated. The o...

Exposure to dust-bound PAHs and associated carcinogenic risk in primitive and traditional cooking practices in Pakistan.

Environ. Sci. Pollut. Res. Int. 22 , 12644-54, (2015)

The aim of this study was to determine the abundance and distribution of polycyclic aromatic hydrocarbons (PAHs) in dust samples collected from the selected professional cooking workplaces (WCs) and r...

更多文献