<生产厂家价格>

克螨特

克螨特用途

Propropgite 可用于杀死螨虫。Propropgite 通过诱导 DNA 损伤来诱导 β 细胞坏死。Propropgite 诱导 MIN6 细胞死亡,IC50 为 1 μM.。

克螨特名称

[ CAS 号 ]:
2312-35-8

[ 中文名 ]:
快螨特

[ 英文名 ]:
2-(4-(tert-Butyl)phenoxy)cyclohexyl prop-2-yn-1-yl sulfite

[中文别名 ]:

[英文别名 ]:

Propargite
d014
do14
Propargiet
(1RS,2RS
comite
EINECS 219-006-1
Omit
BPPS
MFCD00072448

克螨特生物活性

[ 描述 ]:

Propropgite 可用于杀死螨虫。Propropgite 通过诱导 DNA 损伤来诱导 β 细胞坏死。Propropgite 诱导 MIN6 细胞死亡,IC50 为 1 μM.。

[ 相关类别 ]:

研究领域 >> 感染

[参考文献]

[1]. Ting Zhou, et al. A hPSC-based Platform to Discover Gene-Environment Interactions That Impact Human β-cell and Dopamine Neuron Survival. Nat Commun. 2018 Nov 16;9(1):4815.

克螨特物理化学性质

[ 密度 ]:
1.2±0.1 g/cm3

[ 沸点 ]:
450.7±45.0 °C at 760 mmHg

[ 分子式 ]:
C₁₉H₂₆O₄S

[ 分子量 ]:
350.472

[ 闪点 ]:
226.4±28.7 °C

[ 精确质量 ]:
350.155182

[ PSA ]:
63.97000

[ LogP ]:
4.81

[ 外观性状 ]:
暗色液体

[ 蒸汽压 ]:
0.0±1.1 mmHg at 25°C

[ 折射率 ]:
1.561

[ 储存条件 ]:
库房通风低温干燥,与食品原料分开储运

克螨特MSDS

详细MSDS(安全技术说明书)

克螨特毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: WT2900000

CHEMICAL NAME :: Sulfurous acid, 2-(p-tert-butylphenoxy)cyclohexyl-2-propynyl ester

CAS REGISTRY NUMBER :: 2312-35-8

LAST UPDATED :: 199701

DATA ITEMS CITED :: 7

MOLECULAR FORMULA :: C19-H26-O4-S

MOLECULAR WEIGHT :: 350.51

WISWESSER LINE NOTATION :: L6TJ AOSO&O2UU1 BOR DX1&1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1480 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 14,515,1969

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >940 mg/m3/4H

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,719,1991

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 250 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: WRPCA2 World Review of Pest Control. (London, UK) V.1-10, 1962-71. Discontinued. Volume(issue)/page/year: 9,119,1970

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 780 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: TGANAK Tsitologiya i Genetika. Cytology and Genetics. For English translation, see CYGEDX. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1967- Volume(issue)/page/year: 16(1),45,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 10300 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 85JFAN "Agrochemicals Handbook," with updates, Hartley, D., and H. Kidd, eds., Nottingham, Royal Soc. of Chemistry, 1983-86 Volume(issue)/page/year: A589,1985 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989

克螨特安全信息

[ 符号 ]:

GHS05, GHS06, GHS08, GHS09

[ 信号词 ]:
Danger

[ 危害声明 ]:
H315-H318-H331-H351-H410

[ 警示性声明 ]:
P261-P273-P280-P305 + P351 + P338-P311-P501

[ 个人防护装备 ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ 危害码 (欧洲) ]:
T:Toxic

[ 风险声明 (欧洲) ]:
R23;R38;R40;R41;R50/53

[ 安全声明 (欧洲) ]:
S26-S36/37/39-S45-S60-S61

[ 危险品运输编码 ]:
UN 2810

[ RTECS号 ]:
WT2900000

[ 包装等级 ]:
III

[ 危险类别 ]:
9

[ 海关编码 ]:
2920909014

克螨特制备

1.将叔丁醇和氢氧化钠混合，加热至150℃，在1h内滴加1,2-环氧环已烷，保持在150-160℃下反应。滴毕，搅拌半小时，加入二甲苯，冷却至100℃，用浓硫酸中和，蒸除部分二甲苯，带出中和生成的水，即得2. 2-（对-叔丁基苯氧基）环已醇的二甲苯溶液。加热至60℃，在半小时内加氯化亚砜，在5-10℃搅拌2.5h，室外放置15h。再减压加热蒸除挥发性物质，得2-（对-叔丁基苯氧基）环已基氯代磺酸酯。最后，将其加入炔丙醇、吡啶和二甲苯的混合液中，在5-15℃搅拌半小时，用水洗反应物，水层用醚萃取，经后处理，得克螨特。

克螨特海关

[ 海关编码 ]: 2920909014

[ 中文概述 ]:
2920909014 炔螨特。监管条件:S(进出口农药登记证明)。增值税率:17.0%。退税率:9.0%。最低关税:6.5%。普通关税:30.0%

[ Summary ]:
2920909014 2-(4-(tert-butyl)phenoxy)cyclohexyl prop-2-yn-1-yl sulfite。supervision conditions:s(import or export registration certificate for pesticides)。VAT:17.0%。tax rebate rate:9.0%。MFN tarrif:6.5%。general tariff:30.0%

克螨特文献

Permeation of Comite through protective gloves.

J. Hazard. Mater. 137(1) , 165-71, (2006)

The goal of the study was to assess how protective disposable (Safeskin) and chemical protective (Sol-Vex) nitrile gloves were against Comite emulsifiable concentrate formulation containing propargite...

Genotoxic effects of the pesticides Rubigan, Omite and Rovral in root-meristem cells of Crepis capillaris L.

Mutat. Res. 652(2) , 191-7, (2008)

Three pesticides have been studied for their genotoxicity by the use of assays in the plant Crepis capillaris, aimed at measuring chromosomal aberrations, micronuclei and sister chromosome exchange (S...

Toxicity of three acaricides to Tetranychus urticae (Tetranychidae: Acari) and Orius insidiosus (Anthocoridae: Hemiptera).

J. Econ. Entomol. 99(1) , 54-9, (2006)

Management for twospotted spider mite, Tetranychus urticae Koch, populations in peanut, Arachis hypogaea L., relies on acaricides. The outcomes of acaricide applications are most predictable when comp...

更多文献

克螨特