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L-炔丙基甘氨酸

L-炔丙基甘氨酸用途

(S) -2-氨基戊-4-炔酸是一种合成氨基酸。(S) -2-氨基戊-4-炔酸可用于合成叶酸缀合物和相应的金属螯合物[1]。

L-炔丙基甘氨酸名称

[ CAS 号 ]:
23235-01-0

[ 中文名 ]:
(2S)-2-氨基-4-戊炔酸

[ 英文名 ]:
(2S)-2-Amino-4-pentynoic acid

[中文别名 ]:

L-炔丙基甘氨酸

[英文别名 ]:

(S)-alpha-Propargylglycine
(S)-2-Aminopent-4-ynoic acid
(2S)-2-Amino-4-pentynoic acid
L-C-Propargylglycine
MFCD00077855
L-propargyl glycine
(2S)-2-aminopent-4-ynoic acid
4-Pentynoic acid, 2-amino-, (2S)-

L-炔丙基甘氨酸生物活性

[ 描述 ]:

(S) -2-氨基戊-4-炔酸是一种合成氨基酸。(S) -2-氨基戊-4-炔酸可用于合成叶酸缀合物和相应的金属螯合物[1]。

[ 相关类别 ]:

研究领域 >> 其他

信号通路 >> 其他 >> 其他

[参考文献]

[1]. Rudolf Moser, et al.Folate-conjugates and corresponding metal-chelate complexes for use in diagnostic imaging and radiotherapy. WO2008125618A1

L-炔丙基甘氨酸物理化学性质

[ 密度 ]:
1.2±0.1 g/cm3

[ 沸点 ]:
272.1±35.0 °C at 760 mmHg

[ 熔点 ]:
232ºC

[ 分子式 ]:
C₅H₇NO₂

[ 分子量 ]:
113.115

[ 闪点 ]:
118.3±25.9 °C

[ 精确质量 ]:
113.047676

[ PSA ]:
63.32000

[ LogP ]:
-0.03

[ 外观性状 ]:
白色结晶粉末

[ 蒸汽压 ]:
0.0±1.2 mmHg at 25°C

[ 折射率 ]:
1.513

[ 储存条件 ]:
2-8°C

L-炔丙基甘氨酸MSDS

L-炔丙基甘氨酸安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危害码 (欧洲) ]:
Xi

[ 安全声明 (欧洲) ]:
22-24/25

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ 海关编码 ]:
2922499990

L-炔丙基甘氨酸合成路线

L-炔丙基甘氨酸上下游产品

L-炔丙基甘氨酸上游产品

L-炔丙基甘氨酸下游产品

L-炔丙基甘氨酸海关

[ 海关编码 ]: 2922499990

[ 中文概述 ]:
2922499990 其他氨基酸及其酯及它们的盐（含有一种以上含氧基的除外）. 增值税率:17.0% 退税率:9.0% 监管条件:AB(入境货物通关单,出境货物通关单) 最惠国关税:6.5% 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乙醇胺及其盐应报明色度, 乙醇胺及其盐应报明包装

[ 监管条件 ]: A.入境货物通关单 B.出境货物通关单

[ 检验检疫 ]: P.进境动植物、动植物产品检疫 Q.出境动植物、动植物产品检疫 R.进口食品卫生监督检验 S.出口食品卫生监督检验 M.进口商品检验 N.出口商品检验

[ Summary ]:
HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%

L-炔丙基甘氨酸文献

[Hydrogen sulfide inhibits Ca(2+)-induced mitochondrial permeability transition pore opening in spontaneously hypertensive rats].

Fiziol. Zh. 59(1) , 3-10, (2013)

In experiments in vivo and in vitro on the mitochondria isolated from the control and spontaneously hypertensive rats (SHR) hearts, we studied the effects of a donor of hydrogen sulfide (H2S), NaHS, a...

Inhibition of cystathionine gamma-lyase and the biosynthesis of endogenous hydrogen sulphide ameliorates gentamicin-induced nephrotoxicity

Eur. J. Pharmacol. 685(1-3) , 165-73, (2012)

Clinical use of gentamicin over prolonged periods is limited because of dose- and time-dependent nephrotoxicity. Primarily, lysosomal phospholipidosis, intracellular oxidative stress and heightened in...

Interdependency of cystathione γ-lyase and cystathione β-synthase in hydrogen sulfide-induced blood pressure regulation in rats.

Am. J. Hypertens. 25 , 74-81, (2012)

Hydrogen sulfide (H(2)S), an endogenous vasoactive agent, is produced by cystathionine γ-lyase (CGL) and cystathionine β-synthase (CBS) enzymes. This study was conducted to evaluate the relative contr...

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