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N-甲酰甘氨酸

N-甲酰甘氨酸名称

[ CAS 号 ]:
2491-15-8

[ 中文名 ]:
N-甲酰甘氨酸

[ 英文名 ]:
N-Formylglycine

[中文别名 ]:

N-甲酰谷氨酸

[英文别名 ]:

EINECS 219-649-8
N-For-Gly-OH
MFCD00037360
Glycine,N-formyl
N-ForMylglycine
For-Gly-OH
2-Formamidoacetic acid
Formylglycine
Formylglycin
formylaminoacetic acid

N-甲酰甘氨酸物理化学性质

[ 密度 ]:
1.307 g/cm3

[ 沸点 ]:
450.2ºC at 760 mmHg

[ 熔点 ]:
149-151 °C

[ 分子式 ]:
C₃H₅NO₃

[ 分子量 ]:
103.07700

[ 闪点 ]:
226.1ºC

[ 精确质量 ]:
103.02700

[ PSA ]:
66.40000

[ 外观性状 ]:
细白色

[ 蒸汽压 ]:
2.33E-09mmHg at 25°C

[ 折射率 ]:
1.452

[ 储存条件 ]:
2-8°C

N-甲酰甘氨酸MSDS

N-甲酰甘氨酸毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: MC0547000

CHEMICAL NAME :: Glycine, N-formyl-

CAS REGISTRY NUMBER :: 2491-15-8

BEILSTEIN REFERENCE NO. :: 1749108

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C3-H5-N-O3

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >3 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: DZMKAS Deutsche Zahn-, Mund- und Kieferheilkunde. (Leipzig, Ger. Dem. Rep.) V.1-62, 1934-74. Volume(issue)/page/year: 62,32,1974

N-甲酰甘氨酸安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危害码 (欧洲) ]:
Xi: Irritant;

[ 安全声明 (欧洲) ]:
S22-S24/25

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ RTECS号 ]:
MC0547000

[ 海关编码 ]:
2924199090

N-甲酰甘氨酸合成路线

N-甲酰甘氨酸上下游产品

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N-甲酰甘氨酸海关

[ 海关编码 ]: 2924199090

[ 中文概述 ]:
2924199090. 其他无环酰胺（包括无环氨基甲酸酯)(包括其衍生物及盐）. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 包装

[ Summary ]:
2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

N-甲酰甘氨酸文献

New aldehyde tag sequences identified by screening formylglycine generating enzymes in vitro and in vivo.

J. Am. Chem. Soc. 130(37) , 12240-1, (2008)

Formylglycine generating enzyme (FGE) performs a critical posttranslational modification of type I sulfatases, converting cysteine within the motif CxPxR to the aldehyde-bearing residue formylglycine ...

The ribosome as an entropy trap.

Proc. Natl. Acad. Sci. U. S. A. 101(21) , 7897-901, (2004)

To determine the effectiveness of the ribosome as a catalyst, we compared the rate of uncatalyzed peptide bond formation, by the reaction of the ethylene glycol ester of N-formylglycine with Tris(hydr...

Function and structure of a prokaryotic formylglycine-generating enzyme.

J. Biol. Chem. 283(29) , 20117-25, (2008)

Type I sulfatases require an unusual co- or post-translational modification for their activity in hydrolyzing sulfate esters. In eukaryotic sulfatases, an active site cysteine residue is oxidized to t...

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