叠氮磷酸二苯酯(DPPA)

叠氮磷酸二苯酯(DPPA)用途

【用途一】
在有机合成,医药合成及肽类化合物合成方面有广泛应用。叠氮化试剂,用于四苯卟啉-钴催化的烯烃的氮丙啶化。也用作制备大环内酰胺和醛糖还原酶抑制剂的激活剂。也是重要的有机磷试剂。
【用途二】
叠氮化试剂，用于四苯卟啉-钴催化的烯烃的氮丙啶化。也用作制备大环内酰胺和醛糖还原酶抑制剂的激活剂。

叠氮磷酸二苯酯(DPPA)名称

[ CAS 号 ]:
26386-88-9

[ 中文名 ]:
叠氮磷酸二苯酯

[ 英文名 ]:
dppa

[中文别名 ]:

[英文别名 ]:

diphenyl phosphoroazidate
DIPHENYL AZIDOPHOSPHATE
3-(Diphenoxyphosphoryl)-1,2-triazadien-2-ium-1-ide
MFCD00001987
diphenylphosphoric acid amide
Diphenyl Phosphoryl Azide (DPPA)
Diphenyphosphoryl azide
PS-DPPA
Diphenyl phosphorylazide
diphenylphophoryl azide

叠氮磷酸二苯酯(DPPA)物理化学性质

[ 密度 ]:
1.277 g/mL at 25 °C(lit.)

[ 沸点 ]:
157 °C0.17 mm Hg(lit.)

[ 分子式 ]:
C₁₂H₁₀N₃O₃P

[ 分子量 ]:
275.200

[ 闪点 ]:
>230 °F

[ 精确质量 ]:
275.045990

[ PSA ]:
95.09000

[ LogP ]:
2.13

[ 外观性状 ]:
无色或淡黄色液体

[ 折射率 ]:
n20/D 1.551(lit.)

[ 储存条件 ]:
2-8°C

[ 稳定性 ]:
Stable. Incompatible with acids, strong oxidizing agents.

[ 水溶解性 ]:
insoluble

叠氮磷酸二苯酯(DPPA)MSDS

叠氮磷酸二苯酯(DPPA)安全信息

[ 符号 ]:

GHS06

[ 信号词 ]:
Danger

[ 危害声明 ]:
H301 + H311 + H331-H315-H319-H335

[ 警示性声明 ]:
P261-P280-P301 + P310-P305 + P351 + P338-P311

[ 个人防护装备 ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ 危害码 (欧洲) ]:
T:Toxic

[ 风险声明 (欧洲) ]:
R23/24/25;R36/37/38

[ 安全声明 (欧洲) ]:
S26-S36/37/39-S45

[ 危险品运输编码 ]:
UN 3278 6.1/PG 2

[ WGK德国 ]:
3

[ 包装等级 ]:
III

[ 危险类别 ]:
6.1

[ 海关编码 ]:
29299000

叠氮磷酸二苯酯(DPPA)合成路线

叠氮磷酸二苯酯(DPPA)上下游产品

叠氮磷酸二苯酯(DPPA)上游产品

叠氮磷酸二苯酯(DPPA)下游产品

叠氮磷酸二苯酯(DPPA)海关

[ 海关编码 ]: 2931900090

[ 中文概述 ]:
2931900090. 其他有机-无机化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:AB(入境货物通关单,出境货物通关单). 最惠国关税:6.5%. 普通关税:30.0%

[ Summary ]:
2931900090. other organo-inorganic compounds. VAT:17.0%. Tax rebate rate:13.0%. Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward). MFN tariff:6.5%. General tariff:30.0%

叠氮磷酸二苯酯(DPPA)文献

Ultrasonic Nanobubbles Carrying Anti-PSMA Nanobody: Construction and Application in Prostate Cancer-Targeted Imaging.

PLoS ONE 10 , e0127419, (2015)

To facilitate prostate cancer imaging using targeted molecules, we constructed ultrasonic nanobubbles coupled with specific anti-PSMA (prostate specific membrane antigen) nanobodies, and evaluated the...

Use of diphenylphosphorylazide for cross-linking collagen-based biomaterials.

J. Biomed. Mater. Res. 28(2) , 159-65, (1994)

Cross-linking of collagen-based biomaterials increases their strength and persistence in vivo. Recently, we described an efficient cross-linking process via the formation of acyl azide groups on methy...

Guided tissue regeneration using a collagen membrane in chronic adult and rapidly progressive periodontitis patients in the treatment of 3-wall intrabony defects.

J. Clin. Periodontol. 24(8) , 544-9, (1997)

This study, confined to non-smokers, evaluated guided tissue regeneration using a diphenylphosphorylazide-cross-linked bovine type I collagen membrane in deep 3-wall intrabony defects in 52 adult peri...

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