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1-棕榈酰-2-油烯基-sn-甘油-3-磷酰-rac-(1-甘油)钠盐

用途

1-棕榈酰-2-油酰-sn-甘油-3-磷酸-(1'-rac-甘油)钠盐是一种具有一个负电荷的脂质分子,可与肽的正电荷相互作用[1]。

名称

[ CAS 号 ]:
268550-95-4

[ 中文名 ]:
1-棕榈酰基-2-油酰基-sn-甘油-3-磷酸-(1'-rac-甘油)(钠盐)

[ 英文名 ]:
1-palmitoyl-2-oleoyl-sn-glycero-3-phospho-(1′-rac-glycerol) (sodium salt)

[英文别名 ]:

UNII:T52TI8BMQ6
POPG Na,r
16:0-18:1 PG
POPG
1-Palmitoyl-2-oleoyl-phosphatidyl-glycerol sodium
POPG Na,l

生物活性

[ 描述 ]:

1-棕榈酰-2-油酰-sn-甘油-3-磷酸-(1'-rac-甘油)钠盐是一种具有一个负电荷的脂质分子,可与肽的正电荷相互作用[1]。

[ 相关类别 ]:

研究领域 >> 其他

信号通路 >> 其他 >> 其他

[参考文献]

[1]. Kim MR, et al. Co-Encapsulation and Co-Delivery of Peptide Drugs via Polymeric Nanoparticles. Polymers (Basel). 2019;11(2):288. Published 2019 Feb 8.

[2]. Kim MR, et al. Co-Encapsulation and Co-Delivery of Peptide Drugs via Polymeric Nanoparticles. Polymers (Basel). 2019;11(2):288. Published 2019 Feb 8.

物理化学性质

[ 分子式 ]:
C₄₀H₇₆NaO₁₀P

[ 分子量 ]:
770.989

[ 精确质量 ]:
770.507385

[ PSA ]:
161.46000

[ LogP ]:
10.88520

[ 外观性状 ]:
固体;White to Almost white powder to crystal

[ 储存条件 ]:
<0°C;存放于惰性气体之中;避免空气,加热

MSDS

详细MSDS(安全技术说明书)

安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危险品运输编码 ]:
NONH for all modes of transport

文献

Binding properties of antimicrobial agents to lipid membranes using surface plasmon resonance.

Biol. Pharm. Bull. 37(8) , 1383-9, (2014)

In the present study, we examined the interaction of antimicrobial agents with four model lipid membranes that mimicked mammalian cell membranes and Gram-positive and -negative bacterial membranes and...

Characterizing the structure of lipodisq nanoparticles for membrane protein spectroscopic studies.

Biochim. Biophys. Acta 1848(1 Pt B) , 329-33, (2015)

Membrane protein spectroscopic studies are challenging due to the difficulty introduced in preparing homogenous and functional hydrophobic proteins incorporated into a lipid bilayer system. Traditiona...

Detergent-type membrane fragmentation by MSI-78, MSI-367, MSI-594, and MSI-843 antimicrobial peptides and inhibition by cholesterol: a solid-state nuclear magnetic resonance study.

Biochemistry 54(10) , 1897-907, (2015)

Multidrug resistance against the existing antibiotics is becoming a global threat, and any potential drug that can be designed using cationic antimicrobial peptides (AMP) could be an alternate solutio...

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