2-乙酰基-1-B-(L-天冬酰胺)-1,2-双脱氧-D-葡萄糖

更新时间：2024-01-21 10:59:00

2-乙酰基-1-B-(L-天冬酰胺)-1,2-双脱氧-D-葡萄糖结构式	常用名	2-乙酰基-1-B-(L-天冬酰胺)-1,2-双脱氧-D-葡萄糖	英文名	N-Asn
	CAS号	2776-93-4	分子量	335.31000
	密度	1.53g/cm3	沸点	818.5ºC at 760mmHg
	分子式	C₁₂H₂₁N₃O₈	熔点	N/A
	MSDS	中文版美版	闪点	448.8ºC

用途

H-Asn(glcnac-beta-D)-OH是尿中存在的内源性代谢产物,可用于NGLY1-CDDG[1][2]的研究。

中文名	2-乙酰基-1-B-(L-天冬酰胺)-1,2-双脱氧-D-葡萄糖
英文名	N4-(β-N-acetyl-D-glucosaminyl)-L-asparagine
英文别名	更多

描述	H-Asn(glcnac-beta-D)-OH是尿中存在的内源性代谢产物,可用于NGLY1-CDDG[1][2]的研究。
相关类别	研究领域 >> 其他
体外研究	内源性代谢产物被定义为《京都基因和基因组百科全书》注释为我们基因组中约1900种代谢酶的底物或产物。在文献正文中很清楚,许多这些代谢产物都具有毒性[1]。
参考文献	[1]. Lee N, et al. Endogenous toxic metabolites and implications in cancer therapy. Oncogene. 2020 Aug;39(35):5709-5720. [2]. Haijes HA, et al. Aspartylglycosamine is a biomarker for NGLY1-CDDG, a congenital disorder of deglycosylation. Mol Genet Metab. 2019 Aug;127(4):368-372.

密度	1.53g/cm3
沸点	818.5ºC at 760mmHg
分子式	C₁₂H₂₁N₃O₈
分子量	335.31000
闪点	448.8ºC
精确质量	335.13300
PSA	191.44000
蒸汽压	4.86E-31mmHg at 25°C
折射率	1.6
储存条件	2-8°C

危险品运输编码	NONH for all modes of transport
WGK德国	3

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