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2-氨基吖啶酮

2-氨基吖啶酮用途

2-Aminoacridone 是一个广泛用于标记不饱和二糖的荧光团 (λ_exc= 428nm, λ_em= 525nm)。

2-氨基吖啶酮名称

[ CAS 号 ]:
27918-14-5

[ 中文名 ]:
2-氨基吖啶酮

[ 英文名 ]:
2-Aminoacridone

[英文别名 ]:

2-Amino-9(10H)-acridinone
2-amino-10H-acridin-9-one
2-Aminoacridin-9(10H)-one
9(10H)-Acridinone, 2-amino-
2-Amino acridone

2-氨基吖啶酮生物活性

[ 描述 ]:

2-Aminoacridone 是一个广泛用于标记不饱和二糖的荧光团 (λexc= 428nm, λem= 525nm)。

[ 相关类别 ]:

信号通路 >> 其他 >> 其他

染料试剂

研究领域 >> 其他

[体外研究]

通过使用2-氨基吖啶酮(AMAC)作为标记分子,检测GAG衍生的二糖的灵敏度大大提高,分辨率也得到提高[1]。

[参考文献]

[1]. Robert A. M. Vreeburg,et al. Fingerprinting of hydroxyl radical-attacked polysaccharides by N-isopropyl-2-aminoacridone labelling.Biochem J. 2014 Oct 15; 463(Pt 2): 225–237.

[相关活性小分子]

2-氨基吖啶酮物理化学性质

[ 密度 ]:
1.3±0.1 g/cm3

[ 沸点 ]:
442.5±34.0 °C at 760 mmHg

[ 分子式 ]:
C₁₃H₁₀N₂O

[ 分子量 ]:
210.231

[ 闪点 ]:
221.4±25.7 °C

[ 精确质量 ]:
210.079315

[ PSA ]:
58.88000

[ LogP ]:
1.54

[ 蒸汽压 ]:
0.0±1.1 mmHg at 25°C

[ 折射率 ]:
1.690

[ 储存条件 ]:
2-8℃，干燥

2-氨基吖啶酮MSDS

详细MSDS(安全技术说明书)

2-氨基吖啶酮安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H315-H319-H335

[ 警示性声明 ]:
P261-P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xi: Irritant;

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
26-36

[ 危险品运输编码 ]:
NONH for all modes of transport

[ 海关编码 ]:
2933990090

2-氨基吖啶酮合成路线

详细合成路线

2-氨基吖啶酮上下游产品

2-氨基吖啶酮上游产品

2-氨基吖啶酮下游产品

2-氨基吖啶酮海关

[ 海关编码 ]: 2933990090

[ 中文概述 ]:
2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

2-氨基吖啶酮文献

Complex influence of dermatan sulphate on breast cancer cells.

Exp. Biol. Med. (Maywood.) 239(12) , 1575-88, (2014)

Tumor transformation and progression both lead to extracellular matrix remodeling, which is also reflected in an alteration in the proportion of dermatan sulphate (DS) and chondroitin sulphate (CS) an...

FACE analysis as a fast and reliable methodology to monitor the sulfation and total amount of chondroitin sulfate in biological samples of clinical importance.

Molecules 19(6) , 7959-80, (2014)

Glycosaminoglycans (GAGs) due to their hydrophilic character and high anionic charge densities play important roles in various (patho)physiological processes. The identification and quantification of ...

Hyaluronan in cervical epithelia protects against infection-mediated preterm birth.

J. Clin. Invest. 124(12) , 5481-9, (2014)

Increased synthesis of cervical hyaluronan (HA) from early to late pregnancy has long been proposed to play an essential role in disorganization of the collagen-rich extracellular matrix to allow for ...

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